SNCA Antibody
Référence OASG06968
Conditionnement : 100ul
Marque : Aviva Systems Biology
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| Datasheets/Manuals | Printable datasheet for anti-SNCA (OASG06968) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat |
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| Product Format | Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Application | WB, IHC, IF |
| Reconstitution and Storage | Store at -20C. Avoid repeated freeze/thaw cycles. |
| Immunogen | Synthesized peptide derived from human Synuclein- Alpha around the non-phosphorylation site of Y133. Location: 60-140aa. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Specificity | Synuclein- Alpha Polyclonal Antibody detects endogenous levels of Synuclein- Alpha protein. |
| Application Info | WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; |
| Gene Symbol | SNCA |
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| Gene Full Name | synuclein, alpha (non A4 component of amyloid precursor) |
| Alias Symbols | PD1, NACP, PARK1, PARK4 |
| NCBI Gene Id | 6622; 20617; 29219 |
| Description of Target | Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. |
| Uniprot ID | P37840, O55042, P37377 |
| Molecular Weight | 18/14 kDa |
