Sodium dodecyl sulfate [151-21-3]
Référence T20075-25g
Conditionnement : 25g
Marque : TargetMol
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Sodium dodecyl sulfate
(Synonyms: Sodium lauryl sulfate, Sodium dodecylsulfate, SDS, NSC-402488, NSC402488, NSC 402488, Natrium laurylsulfuricum, Laurylsulfuric acid sodium salt, Anticerumen) Copy Product Info
Sodium dodecyl sulfate(Sodium lauryl sulfate) is a pharmaceutical excipient that is biologically inactive and improves the stability, solubility and processability of pharmaceutical preparations.
Cas No. 151-21-3
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.75%
Appearance:Solid
Color:White
COA HNMR LCMS
Product Introduction
Sodium dodecyl sulfate AI Summary
Sodium dodecyl sulfate exhibits a diverse range of biological activities. It demonstrates a dose-dependent hemolytic effect on rat red blood cells, with hemolysis increasing from 12.25% at 1 mM concentration to 62.66% at 5 mM. In antimicrobial studies, it shows significant activity against various strains of Escherichia coli, including multidrug-resistant strains, with Minimum Inhibitory Concentration (MIC) values ranging from 62.5 µg/mL to 128.0 µg/mL. It also exhibits antibacterial activity against Enterobacter cloacae, Enterococcus faecalis, Proteus mirabilis, and methicillin-resistant Staphylococcus aureus, and antifungal activity against Candida species. Additionally, it has potent anti-inflammatory properties by inhibiting IL1alpha release in a reconstituted human epidermis model. In terms of cytotoxicity, Sodium dodecyl sulfate is highly potent against human HepG2/C3A cells with an IC50 value of 0.222 nM, and it shows lesser toxicity against mouse RAW264.7 and human HCT116 cells, with IC50 values greater than 100,000 nM. The compound also presents impacting activities against Steinernema feltiae in nematicidal assays and induces membrane permeabilization. Biosurfactant properties are indicated by its ability to lower surface tension, with a critical micelle concentration (CMC) of 8.2 mM and activity in oil displacement assays. Furthermore, it displays significant inhibition of full-length human soluble epoxide hydrolase phosphatase activity, stabilizing the phosphatase domain while showing weaker activity against the hydrolase domain. Sodium dodecyl sulfate's broad spectrum of activities position it as a potential candidate for therapeutic applications involving antimicrobial, anti-inflammatory, and cytotoxic properties..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Sodium dodecyl sulfate(Sodium lauryl sulfate) is a pharmaceutical excipient that is biologically inactive and improves the stability, solubility and processability of pharmaceutical preparations. |
| Synonyms | Sodium lauryl sulfate, Sodium dodecylsulfate, SDS, NSC-402488, NSC402488, NSC 402488, Natrium laurylsulfuricum, Laurylsulfuric acid sodium salt, Anticerumen |
| Molecular Weight | 288.38 |
| Formula | C12H25NaO4S |
| Cas No. | 151-21-3 |
| Smiles | O=S([O-])(OCCCCCCCCCCCC)=O.[Na+] |
| Relative Density. | 1.03 g/cm3 at 20℃ |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 60 mg/mL (208.06 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | ||||||||||||||||||||||||||||||||||||