SOX6 Antibody
Référence MBS8582404-0,1mL-FITC
Conditionnement : 0.1mL(FITC)
Marque : MyBiosource
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SOX6 Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8582404MBS8582404 is an antibody targeting SOX6. Also known as SOX6 Antibody. Reactive in Human, Mouse, Rat, Bovine, Dog, Monkey, Pig. Host: Rabbit. Rabbit polyclonal antibody to SOX6 More details
Product Overview
Online Datasheet in PDFProduct Name
SOX6, Polyclonal Antibody
Full Product Name
SOX6 Antibody
Product Gene Name
anti-SOX6 antibody
Product Synonym Names
Transcription factor SOX-6
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Bovine, Dog, Monkey, Pig
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of SOX6 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Molecular Weight
91,921 Da
Chromosome Location
Chromosome: 11; NC_000011.9 (15987995..16497935, complement). Location: 11p15.3
OMIM
607257
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human SOX6. The exact sequence is proprietary.
Product Categories/Family for anti-SOX6 antibody
Primary Antibody
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-SOX6 antibody
Western Blot (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)
Application Notes for anti-SOX6 antibody
WB: 1:500-1:1000
IHC: 1:50-1:200
ChIP: Use at an assay dependent concentration
IHC: 1:50-1:200
ChIP: Use at an assay dependent concentration
Other Notes
Small volumes of anti-SOX6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for SOX6. It may not necessarily be applicable to this product.
NCBI Official Full Name
transcription factor SOX-6 isoform 3
NCBI Official Synonym Full Names
SRY (sex determining region Y)-box 6
NCBI Official Symbol
SOX6
NCBI Official Synonym Symbols
SOXD; HSSOX6
UniProt Protein Name
Transcription factor SOX-6
Protein Family
Transcription factor
UniProt Gene Name
SOX6
UniProt Entry Name
SOX6_HUMAN
NCBI Protein Information
transcription factor SOX-6; SRY-box containing gene 6
NCBI Summary for SOX6
This gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. The encoded protein is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. The encoded protein interacts with other family members to cooperatively activate gene expression. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]
Show more UniProt Comments for SOX6
SOX6: Transcriptional activator. Binds specifically to the DNA sequence 5'-AACAAT-3'. Plays a key role in several developmental processes, including neurogenesis and skeleton formation. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 11p15.3
Cellular Component: nucleoplasm; nucleus
Molecular Function: protein binding; DNA binding; protein heterodimerization activity; sequence-specific DNA binding; transcription factor activity
Biological Process: muscle development; erythrocyte development; transcription, DNA-dependent; in utero embryonic development; cell morphogenesis; gene silencing; negative regulation of transcription from RNA polymerase II promoter; oligodendrocyte cell fate specification; cardiac muscle cell differentiation; post-embryonic development; positive regulation of chondrocyte differentiation; regulation of transcription, DNA-dependent; astrocyte differentiation; cartilage development; positive regulation of transcription from RNA polymerase II promoter
Show more Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 11p15.3
Cellular Component: nucleoplasm; nucleus
Molecular Function: protein binding; DNA binding; protein heterodimerization activity; sequence-specific DNA binding; transcription factor activity
Biological Process: muscle development; erythrocyte development; transcription, DNA-dependent; in utero embryonic development; cell morphogenesis; gene silencing; negative regulation of transcription from RNA polymerase II promoter; oligodendrocyte cell fate specification; cardiac muscle cell differentiation; post-embryonic development; positive regulation of chondrocyte differentiation; regulation of transcription, DNA-dependent; astrocyte differentiation; cartilage development; positive regulation of transcription from RNA polymerase II promoter
Research Articles on SOX6
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-SOX6 antibody
| Reference Product | PubMed Publications |
|---|---|
| SOX5 antibody | >71 publications with SOX6 and SOX5 |
| SUMO2 antibody | >1 publications with SOX6 and SUMO2 |
| CTBP2 antibody | >1 publications with SOX6 and CTBP2 |
Pathways associated with anti-SOX6 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Endochondral Ossification Pathway antibodies | Endochondral Ossification Pathway Diagram |
Diseases associated with anti-SOX6 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Musculoskeletal Diseases Antibodies | >21 publications with SOX6 and Musculoskeletal Diseases |
| Neoplasms Antibodies | >14 publications with SOX6 and Neoplasms |
| Hypertrophy Antibodies | >11 publications with SOX6 and Hypertrophy |
| Heart Diseases Antibodies | >5 publications with SOX6 and Heart Diseases |
| Congenital Abnormalities Antibodies | >5 publications with SOX6 and Congenital Abnormalities |
| Brain Diseases Antibodies | >5 publications with SOX6 and Brain Diseases |
| Disease Models, Animal Antibodies | >3 publications with SOX6 and Disease Models, Animal |
| Hypertension Antibodies | >3 publications with SOX6 and Hypertension |
| Carcinoma, Hepatocellular Antibodies | >2 publications with SOX6 and Carcinoma, Hepatocellular |
| Abnormalities, Multiple Antibodies | >1 publications with SOX6 and Abnormalities, Multiple |
Organs/Tissues associated with anti-SOX6 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Bone Antibodies | >59 publications with SOX6 and Bone |
| Connective Tissue Antibodies | >33 publications with SOX6 and Connective Tissue |
| Embryonic Tissue Antibodies | >29 publications with SOX6 and Embryonic Tissue |
| Muscle Antibodies | >25 publications with SOX6 and Muscle |
| Blood Antibodies | >15 publications with SOX6 and Blood |
| Testis Antibodies | >13 publications with SOX6 and Testis |
| Brain Antibodies | >13 publications with SOX6 and Brain |
| Heart Antibodies | >10 publications with SOX6 and Heart |
| Nerve Antibodies | >8 publications with SOX6 and Nerve |
| Liver Antibodies | >7 publications with SOX6 and Liver |