SOX8 Antibody
Référence MBS8583809-0,1mL-HRP
Conditionnement : 0.1mL(HRP)
Marque : MyBiosource
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SOX8 Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8583809MBS8583809 is an antibody targeting SOX8. Also known as SOX8 Antibody. Reactive in Human, Mouse, Rat, Chicken, Pig, Zebrafish. Host: Rabbit. Rabbit polyclonal antibody to SOX8 More details
Product Overview
Online Datasheet in PDFProduct Name
SOX8, Polyclonal Antibody
Full Product Name
SOX8 Antibody
Product Gene Name
anti-SOX8 antibody
Product Synonym Gene Name
SOX8, SOX9, SOX17, SOX18
Product Synonym Names
SOX8; Transcription factor SOX-8; SOX9; Transcription factor SOX-9; SOX17; Transcription factor SOX-17; SOX18; Transcription factor SOX-18
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Chicken, Pig, Zebrafish
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of SOX8 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Molecular Weight
446
OMIM
605923
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human SOX8. The exact sequence is proprietary.
Product Categories/Family for anti-SOX8 antibody
Primary Antibody
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-SOX8 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-SOX8 antibody
WB: 1:500-1:1000
IHC: 1:50-1:200
IHC: 1:50-1:200
Other Notes
Small volumes of anti-SOX8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for SOX8. It may not necessarily be applicable to this product.
NCBI Official Full Name
Transcription factor SOX-8
NCBI Official Synonym Full Names
SRY (sex determining region Y)-box 8
NCBI Official Symbol
SOX8
UniProt Protein Name
Transcription factor SOX-8
Protein Family
Transcription factor
UniProt Gene Name
SOX8
UniProt Entry Name
SOX8_HUMAN
NCBI Protein Information
transcription factor SOX-8
NCBI Summary for SOX8
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome). [provided by RefSeq, Jul 2008]
Show more UniProt Comments for SOX8
SOX8: May play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3'.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 16p13.3
Cellular Component: cytoplasm; nucleus
Molecular Function: DNA binding; protein heterodimerization activity; transcription factor binding
Biological Process: negative regulation of photoreceptor cell differentiation; transcription from RNA polymerase II promoter; fat cell differentiation; cell fate commitment; positive regulation of gliogenesis; in utero embryonic development; astrocyte fate commitment; positive regulation of transcription, DNA-dependent; male gonad development; cell maturation; signal transduction; Sertoli cell development; enteric nervous system development; peripheral nervous system development; osteoblast differentiation; retina development in camera-type eye; positive regulation of osteoblast proliferation; oligodendrocyte differentiation; spermatogenesis; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; negative regulation of myoblast differentiation; neural crest cell migration; negative regulation of apoptosis
Show more Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 16p13.3
Cellular Component: cytoplasm; nucleus
Molecular Function: DNA binding; protein heterodimerization activity; transcription factor binding
Biological Process: negative regulation of photoreceptor cell differentiation; transcription from RNA polymerase II promoter; fat cell differentiation; cell fate commitment; positive regulation of gliogenesis; in utero embryonic development; astrocyte fate commitment; positive regulation of transcription, DNA-dependent; male gonad development; cell maturation; signal transduction; Sertoli cell development; enteric nervous system development; peripheral nervous system development; osteoblast differentiation; retina development in camera-type eye; positive regulation of osteoblast proliferation; oligodendrocyte differentiation; spermatogenesis; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; negative regulation of myoblast differentiation; neural crest cell migration; negative regulation of apoptosis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-SOX8 antibody
| Reference Product | PubMed Publications |
|---|---|
| JUN antibody | >12 publications with SOX8 and JUN |
| NR5A1 antibody | >2 publications with SOX8 and NR5A1 |
| PAX3 antibody | >2 publications with SOX8 and PAX3 |
| EGR2 antibody | >1 publications with SOX8 and EGR2 |
| OLIG2 antibody | >1 publications with SOX8 and OLIG2 |
Diseases associated with anti-SOX8 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Nervous System Diseases Antibodies | >10 publications with SOX8 and Nervous System Diseases |
| Congenital Abnormalities Antibodies | >5 publications with SOX8 and Congenital Abnormalities |
| Abnormalities, Multiple Antibodies | >4 publications with SOX8 and Abnormalities, Multiple |
| Brain Diseases Antibodies | >3 publications with SOX8 and Brain Diseases |
| Peripheral Nervous System Diseases Antibodies | >3 publications with SOX8 and Peripheral Nervous System Diseases |
| Disease Models, Animal Antibodies | >2 publications with SOX8 and Disease Models, Animal |
| Carcinoma, Hepatocellular Antibodies | >1 publications with SOX8 and Carcinoma, Hepatocellular |
| Neural Tube Defects Antibodies | >1 publications with SOX8 and Neural Tube Defects |
| Nerve Degeneration Antibodies | >1 publications with SOX8 and Nerve Degeneration |
| Multiple Myeloma Antibodies | >1 publications with SOX8 and Multiple Myeloma |
Organs/Tissues associated with anti-SOX8 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Testis Antibodies | >27 publications with SOX8 and Testis |
| Embryonic Tissue Antibodies | >17 publications with SOX8 and Embryonic Tissue |
| Brain Antibodies | >13 publications with SOX8 and Brain |
| Nerve Antibodies | >8 publications with SOX8 and Nerve |
| Heart Antibodies | >6 publications with SOX8 and Heart |
| Eye Antibodies | >6 publications with SOX8 and Eye |
| Ganglia Antibodies | >5 publications with SOX8 and Ganglia |
| Intestine Antibodies | >1 publications with SOX8 and Intestine |