SPHK1 Mouse Monoclonal Antibody [Clone ID: OTI1A6]
CAT#: TA507215
SPHK1 mouse monoclonal antibody, clone OTI1A6 (formerly 1A6)
Size: 30 ul
Formulation: Carrier-Free
Conjugation: Biotin HRP
Specifications
| Product Data | |
| Clone Name | OTI1A6 |
| Applications | IF, IHC, WB |
| Recommended Dilution | WB 1:400~4000, IHC 1:150, IF 1:100 |
| Reactivities | Human |
| Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human SPHK1(NP_068807) produced in HEK293T cell. |
| Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Predicted Protein Size | 43.8 kDa |
| Gene Name | sphingosine kinase 1 |
| Database Link | |
| Background | The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |
| Synonyms | SPHK |
| Reference Data | |
| Protein Families | Druggable Genome |
| Protein Pathways | Calcium signaling pathway, Fc gamma R-mediated phagocytosis, Metabolic pathways, Sphingolipid metabolism, VEGF signaling pathway |
Documents
| Product Manuals |
| FAQs |
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| SDS |
Resources
| Antibody Resources |
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Other Versions
| SKU | Description | Size | |
|---|---|---|---|
| CF507215 | Carrier-free (BSA/glycerol-free) SPHK1 mouse monoclonal antibody, clone OTI1A6 (formerly 1A6) | 600,00 EUR | |
| TA507215AM | SPHK1 mouse monoclonal antibody, clone OTI1A6 (formerly 1A6), Biotinylated | 509,00 EUR | |
| TA507215BM | SPHK1 mouse monoclonal antibody, clone OTI1A6 (formerly 1A6), HRP conjugated | 509,00 EUR | |
| TA507215S | SPHK1 mouse monoclonal antibody, clone OTI1A6 (formerly 1A6) | 200,00 EUR |