Sterigmatocystine [10048-13-2]
Référence T16942-10mg
Conditionnement : 10mg
Marque : TargetMol
Contactez votre distributeur local :
Téléphone : +1 850 650 7790
Sterigmatocystine
Copy Product InfoSterigmatocystine is an inhibitor of G1 Phase and DNA synthesis and is used to inhibit p21 activity. Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor.
Cas No. 10048-13-2
For research use only—not for human use. No sales to individuals. Use as intended only.
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Sterigmatocystine is an inhibitor of G1 Phase and DNA synthesis and is used to inhibit p21 activity. Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor. |
| In vitro | Sterigmatocystine-induced DNA damage activates the ATM/53-dependent signaling pathway, leading to G2 arrest in GES-1 cells [4]. |
| In vivo | Sterigmatocystine (ip; 3 mg/kg once daily for 14 days) suppresses p21WAF1/CIP1 [3]. |
| Molecular Weight | 324.28 |
| Formula | C18H12O6 |
| Cas No. | 10048-13-2 |
| Smiles | 12[C@]12OC=C[C@@]1(12)c1c(O2)cc(OC)c2c1oc1cccc(O)c1c2=O |
| Relative Density. | 1.51 g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |