STMN1 Antibody

Référence MBS8582409-0,1mL-Biotin

Conditionnement : 0.1mL(Biotin)

Marque : MyBiosource

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STMN1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8582409

MBS8582409 is an antibody targeting STMN1. Also known as STMN1 Antibody. Reactive in Human, Mouse, Rat, Bovine, Dog, Monkey, Pig, Rabbit, Sheep. Host: Rabbit. Rabbit polyclonal antibody to STMN1 More details

Product Overview

Online Datasheet in PDF
Product Name
STMN1, Polyclonal Antibody
Full Product Name
STMN1 Antibody
Product Gene Name
anti-STMN1 antibody
Product Synonym Names
C1orf215; LAP18; OP18; Stathmin; Leukemia-associated phosphoprotein p18; Metablastin; Oncoprotein 18; Op18; Phosphoprotein p19; pp19; Prosolin; Protein Pr22; pp17
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Bovine, Dog, Monkey, Pig, Rabbit, Sheep
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of STMN1 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Molecular Weight
17,303 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (26210677..26233368, complement). Location: 1p36.11
OMIM
151442
3D Structure
ModBase 3D Structure for P16949
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human STMN1. The exact sequence is proprietary.

Product Categories/Family for anti-STMN1 antibody

Primary Antibody
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-STMN1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
Application Notes for anti-STMN1 antibody
WB: 1:500-1:1000
IHC: 1:50-1:200

Other Notes

Small volumes of anti-STMN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for STMN1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
stathmin isoform b
NCBI Official Synonym Full Names
stathmin 1
NCBI Official Symbol
STMN1
NCBI Official Synonym Symbols
Lag; SMN; OP18; PP17; PP19; PR22; LAP18; C1orf215
UniProt Protein Name
Stathmin
UniProt Synonym Protein Names
Leukemia-associated phosphoprotein p18; Metablastin; Oncoprotein 18; Op18; Phosphoprotein p19; pp19; Prosolin; Protein Pr22; pp17
Protein Family
Stathmin
UniProt Gene Name
STMN1
UniProt Synonym Gene Names
C1orf215; LAP18; OP18; Op18; pp19
UniProt Entry Name
STMN1_HUMAN
NCBI Protein Information
stathmin; prosolin; metablastin; oncoprotein 18; phosphoprotein 19; phosphoprotein p19; stathmin 1/oncoprotein 18; transmembrane protein C1orf215; leukemia-associated phosphoprotein p18

NCBI Summary for STMN1

This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
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UniProt Comments for STMN1

STMN1: a microtubule-associated protein involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Phosphorylation reduces tubulin binding 10-fold and suppresses the MT polymerization inhibition activity. Present in much greater abundance in cells from patients with acute leukemia of different subtypes than in normal peripheral blood lymphocytes, nonleukemic proliferating lymphoid cells, bone marrow cells, or cells from patients with chronic lymphoid or myeloid leukemia.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 1p36.11

Cellular Component: microtubule; neuron projection; membrane; cytoplasm; intracellular; cytosol

Molecular Function: tubulin binding; signal transducer activity

Biological Process: mitotic spindle organization and biogenesis; axonogenesis; negative regulation of microtubule polymerization; response to virus; microtubule depolymerization; positive regulation of cell motility; brain development; signal transduction; neurite development; regulation of cytoskeleton organization and biogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-STMN1 antibody

 Reference Product  PubMed Publications
 CDKN1B antibody  >5 publications with STMN1 and CDKN1B
 STAT3 antibody  >2 publications with STMN1 and STAT3
 MAPK3 antibody  >2 publications with STMN1 and MAPK3
 UHMK1 antibody  >1 publications with STMN1 and UHMK1
 HSPA8 antibody  >1 publications with STMN1 and HSPA8
 CDK1 antibody  >1 publications with STMN1 and CDK1

Pathways associated with anti-STMN1 antibody

 Products by Pathway  Pathway Diagram
 Aurora B Signaling Pathway antibodies  Aurora B Signaling Pathway Diagram
 Integrated Pancreatic Cancer Pathway antibodies  Integrated Pancreatic Cancer Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 Regulation Of Microtubule Cytoskeleton Pathway antibodies  Regulation Of Microtubule Cytoskeleton Pathway Diagram
 Signaling Mediated By P38-gamma And P38-delta Pathway antibodies  Signaling Mediated By P38-gamma And P38-delta Pathway Diagram

Diseases associated with anti-STMN1 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >131 publications with STMN1 and Neoplasms
 Carcinoma Antibodies  >46 publications with STMN1 and Carcinoma
 Breast Neoplasms Antibodies  >25 publications with STMN1 and Breast Neoplasms
 Neoplasm Metastasis Antibodies  >17 publications with STMN1 and Neoplasm Metastasis
 Adenocarcinoma Antibodies  >16 publications with STMN1 and Adenocarcinoma
 Cell Transformation, Neoplastic Antibodies  >10 publications with STMN1 and Cell Transformation, Neoplastic
 Lung Neoplasms Antibodies  >10 publications with STMN1 and Lung Neoplasms
 Prostatic Neoplasms Antibodies  >10 publications with STMN1 and Prostatic Neoplasms
 Neoplasms, Experimental Antibodies  >9 publications with STMN1 and Neoplasms, Experimental
 Carcinoma, Squamous Cell Antibodies  >8 publications with STMN1 and Carcinoma, Squamous Cell

Organs/Tissues associated with anti-STMN1 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >45 publications with STMN1 and Brain
 Blood Antibodies  >40 publications with STMN1 and Blood
 Nerve Antibodies  >35 publications with STMN1 and Nerve
 Lung Antibodies  >17 publications with STMN1 and Lung
 Lymph Node Antibodies  >15 publications with STMN1 and Lymph Node
 Lymph Antibodies  >15 publications with STMN1 and Lymph
 Prostate Antibodies  >15 publications with STMN1 and Prostate
 Liver Antibodies  >13 publications with STMN1 and Liver
 Bone Antibodies  >8 publications with STMN1 and Bone
 Kidney Antibodies  >7 publications with STMN1 and Kidney