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> STRO-1 Mouse Monoclonal Antibody [Clone ID: STRO-1]

STRO-1 Mouse Monoclonal Antibody [Clone ID: STRO-1]

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Référence AM26067PU-N

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STRO-1 Mouse Monoclonal Antibody [Clone ID: STRO-1]

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SKU
AM26067PU-N
STRO-1 mouse monoclonal antibody, clone STRO-1, Aff - Purified
Size:
100 ug
Conjugation:
Unconjugated APC PE
 
Specifications
Product Data
Clone Name STRO-1
Application FC, IF
Recommended Dilution Flow Cytometry.
Immunocytochemistry.
Reactivity Human
Antibody Host Mouse
Isotype IgM
Clonality Monoclonal
Immunogen Human CD34 positive bone marrow cells.
Specificity This antibody recognizes the cell surface antigen STRO1 expressed by bone marrow mesenchymal stromal cells and nucleated erythroid precursors, but not by committed hematopoietic progenitors.
Buffer Tris buffered saline (TBS), pH~8.0
State: Aff - Purified
State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
Preservative: 15mM Sodium Azide
Concentration lot specific
Purification Precipitation Methods and Ion Exchange Chromatography
Conjugation Unconjugated
Storage Store undiluted at 2-8°C.
DO NOT FREEZE!
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Background STRO-1 is a cell surface antigen expressed by stromal elements in human bone marrow, identified by monoclonal antibody STRO-1. Approximately 10% of mononuclear cells, greater than 95% of which are nucleated erythroid precursors, are STRO-1 positive, whereas the CFU-GM (colony-forming unit granulocyte-macrophage), BFU-E (erythroid burst) and CFU-Mix (mixed colonies) committed progenitor cells are negative. CFU-F (fibroblast colony-forming cells) are present exclusively in the STRO-1 positive population. When plated under long-term bone marrow culture conditions, STRO-1 positive cells generate adherent cell layers containing multiple stromal cell types, including adipocytes, smooth muscle cells, osteoblasts, chondrocytes, and fibroblastic elements. In combination with glycophorin A, STRO-1 is a useful marker for identification of mesenchymal stem cells. STRO-1 and CD117 are markers for osteosarcoma cells.
Reference Data
Product Manuals
FAQs
  • Antibody and Western Standard
SDS

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