Synapsin1 (Ab-62) Antibody
Référence MBS859720-0,1mL-PE
Conditionnement : 0.1mL(PE)
Marque : MyBiosource
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Peptide-+
Immunohistochemistry analysis of paraffin-embedded human brain tissue using Synapsin1 (Ab-62) antibody. Western blot analysis of extracts from NIH/3T3 cells, treated with Nocodazole (1mug/ml, 16hours), using Synapsin1 (Ab-62) antibody.
Synapsin1 (SYN-1) Antibody
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS859720MBS859720 is an antibody targeting SYN-1. Also known as Synapsin1 (Ab-62) Antibody. Reactive in Human, Mouse, Rat. More details
Product Overview
Online Datasheet in PDFProduct Name
Synapsin1 (SYN-1), Antibody
Full Product Name
Synapsin1 (Ab-62) Antibody
Product Gene Name
anti-SYN-1 antibody
Product Synonym Names
Brain protein 4.1; synapsin I
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
Synapsin1 (Ab-62) antibody detects endogenous levels of total Synapsin1 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
70,033 Da
OMIM
300491
Immunogen
The antiserum was produced against synthesized non-phosphopeptide derived from human Synapsin1 around the phosphorylation site of serine 62 (V-A-SP-P-A).
Product Categories/Family for anti-SYN-1 antibody
Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-SYN-1 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-SYN-1 antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:1000
IHC: 1:50~1:100
ELISA: 1:1000
Product References and Citations for anti-SYN-1 antibody
Kun Jiang, Blood, Jan 2003; 101: 236-244. Joseph Fargnoli, J. Biol. Chem., Nov 1995; 270: 26533. Attila Mócsai, Blood, May 2003; 101: 4155-4163. Takechiyo Yamada, J. Immunol., Jul 2001; 167: 283.
Other Notes
Small volumes of anti-SYN-1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for SYN-1. It may not necessarily be applicable to this product.
NCBI Official Full Name
synapsin-1 isoform Ia
NCBI Official Synonym Full Names
synapsin I
NCBI Official Symbol
SYN1
NCBI Official Synonym Symbols
SYNI; SYN1a; SYN1b
UniProt Protein Name
Synapsin-1
UniProt Synonym Protein Names
Brain protein 4.1; Synapsin I
UniProt Gene Name
SYN1
NCBI Protein Information
synapsin-1
NCBI Summary for SYN-1
This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Show more UniProt Comments for SYN-1
Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-SYN-1 antibody
| Reference Product | PubMed Publications |
|---|---|
| SYN2 antibody | >14 publications with SYN-1 and SYN2 |
| SYN3 antibody | >7 publications with SYN-1 and SYN3 |
| PAK3 antibody | >1 publications with SYN-1 and PAK3 |
Pathways associated with anti-SYN-1 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| BDNF Signaling Pathway antibodies | BDNF Signaling Pathway Diagram |
| Dopamine Neurotransmitter Release Cycle Pathway antibodies | Dopamine Neurotransmitter Release Cycle Pathway Diagram |
| Monoamine Transport Pathway antibodies | Monoamine Transport Pathway Diagram |
| Neuronal System Pathway antibodies | Neuronal System Pathway Diagram |
| Neurotransmitter Release Cycle Pathway antibodies | Neurotransmitter Release Cycle Pathway Diagram |
| Serotonin Neurotransmitter Release Cycle Pathway antibodies | Serotonin Neurotransmitter Release Cycle Pathway Diagram |
| Synaptic Vesicle Pathway antibodies | Synaptic Vesicle Pathway Diagram |
| Transmission Across Chemical Synapses Pathway antibodies | Transmission Across Chemical Synapses Pathway Diagram |
Diseases associated with anti-SYN-1 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Mental Disorders Antibodies | >9 publications with SYN-1 and Mental Disorders |
| Neoplasms Antibodies | >6 publications with SYN-1 and Neoplasms |
| Brain Diseases Antibodies | >6 publications with SYN-1 and Brain Diseases |
| Central Nervous System Diseases Antibodies | >5 publications with SYN-1 and Central Nervous System Diseases |
| Neurobehavioral Manifestations Antibodies | >4 publications with SYN-1 and Neurobehavioral Manifestations |
| Cognition Disorders Antibodies | >3 publications with SYN-1 and Cognition Disorders |
| Seizures Antibodies | >3 publications with SYN-1 and Seizures |
| Learning Disorders Antibodies | >3 publications with SYN-1 and Learning Disorders |
| Necrosis Antibodies | >3 publications with SYN-1 and Necrosis |
| Memory Disorders Antibodies | >2 publications with SYN-1 and Memory Disorders |
Organs/Tissues associated with anti-SYN-1 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >23 publications with SYN-1 and Brain |
| Nerve Antibodies | >6 publications with SYN-1 and Nerve |
| Testis Antibodies | >3 publications with SYN-1 and Testis |
| Placenta Antibodies | >2 publications with SYN-1 and Placenta |
| Eye Antibodies | >2 publications with SYN-1 and Eye |
| Connective Tissue Antibodies | >1 publications with SYN-1 and Connective Tissue |
| Lung Antibodies | >1 publications with SYN-1 and Lung |