Tauro-Obeticholic acid [863239-61-6]

Référence T13092-10mg

Conditionnement : 10mg

Marque : TargetMol

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Tauro-Obeticholic acid

Copy Product Info
Tauro-Obeticholic acid is an active Obeticholic acid metabolite. Obeticholic acid is an orally bioavailable agonist of farnesoid-X receptor (FXR).
Tauro-Obeticholic acid
Cas No. 863239-61-6
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.82%
Appearance:Solid
Color:White
COA HNMR HPLC

Product Introduction

Bioactivity
Description
Tauro-Obeticholic acid is an active Obeticholic acid metabolite. Obeticholic acid is an orally bioavailable agonist of farnesoid-X receptor (FXR).
In vitro
Obeticholic acid and taurine are conjugated in the liver to form taurine-obeticholic acid, which is secreted into the bile. Microorganisms in the ileum and colon can dissociate taurine-cholesteric acid and convert it into the parent drug, which can then be reabsorbed or excreted in feces.
Chemical Properties
Molecular Weight527.76
FormulaC28H49NO6S
Cas No.863239-61-6
Smiles19[C@@]12CC[C@H]([C@H](C)CCC(=O)NCCS(O)(=O)=O)[C@@]1(C)CC[C@@]1(19)[C@@]2(19)[C@H](O)[C@H](CC)[C@]2(19)C[C@H](O)CC[C@]12C
Relative Density.1.177 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (94.74 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.8948 mL9.4740 mL18.9480 mL94.7400 mL
5 mM0.3790 mL1.8948 mL3.7896 mL18.9480 mL
10 mM0.1895 mL0.9474 mL1.8948 mL9.4740 mL
20 mM0.0947 mL0.4737 mL0.9474 mL4.7370 mL
50 mM0.0379 mL0.1895 mL0.3790 mL1.8948 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.