Thy1 rat monoclonal antibody, clone G7, Low Endotoxin
Size:
500 ug
Conjugation:
Unconjugated
View other "Thy1 or NP_033408.1" antibodies
Specifications
Product Data
Clone Name
G7
Application
FC
Recommended Dilution
Flow Cytometry. (Ref.1,10) Immunohistochemistry (Acetone-Fixed, Frozen Sections). (Ref.10) In vitro T Cell Activation. (Ref.1,5,6,9) Induction of apoptosis.
Reactivity
Mouse
Antibody Host
Rat
Isotype
IgG2c
Clonality
Monoclonal
Specificity
This antibody recognises Thy-1.1 and Thy-1.2 alloantigens (Thy-1 epitope region A). MAb G7 stimulates T-cell proliferation and IL-2 secretion, via signalling through the T-cell receptor/CD3 complex. (Ref.1,5-7). It has also been reported to promote apoptosis of thymocytes and CTL clones (Ref.4,7) and to mediate adhesion of thymocytes to thymic stroma. (Ref.8)
CD90/Thy-1, a GPI-anchored molecule and one of the smallest members of the immunoglobulin superfamily of cell surface receptors, consists of a single V-set domain. (Ref.1-4) It is expressed on thymocytes, peripheral T lymphocytes, some intraepithelial T lymphocytes and neurons of all mouse strains. (Ref.1,2)
Synonyms
Thy-1, THY1, CDw90
Reference Data
Protein Categories
CD Markers, Intracellular Proteins, Membrane Proteins
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