WNT7A Antibody

Référence MBS8516772-0,1mL-AF647

Conditionnement : 0.1mL(AF647)

Marque : MyBiosource

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WNT7A Antibody – Rabbit

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8516772

Background: Protein Wnt-7a; wnt 7a;Protein Wnt-7a precursor; proto-oncogene wnt7a protein; wingless-type MMTV integration site family, member 7A; WNT7A; WNT7A_HUMAN More details

Product Overview

Online Datasheet in PDF
Product Name
WNT7A, Antibody
Full Product Name
WNT7A Antibody
Product Gene Name
anti-WNT7A antibody
Product Synonym Names
Protein Wnt-7a; wnt 7a;Protein Wnt-7a precursor; proto-oncogene wnt7a protein;wingless-type MMTV integration site family, member 7A; WNT7A; WNT7A_HUMAN.
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit
Form/Format
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Purity/Purification
Affinity purified by Protein A
Specificity
WNT7A Antibody detects endogenous levels of total WNT7A
Preparation and Storage
Store at -20? for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4°C.
OMIM
228930
3D Structure
ModBase 3D Structure for O00755
Immunogen
KLH conjugated synthetic peptide derived from human WNT7A 241-349/349
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-WNT7A antibody
Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-WNT7A antibody

Western blot analysis of extracts of mouse kidneycell lines, using WNT7A antibody.
Rabbit Anti-WNT7A Antibody – Cat# MBS8516772

Other Notes

Small volumes of anti-WNT7A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for WNT7A purchase

MBS8516772 is an antibody targeting WNT7A. Also known as WNT7A Antibody. Reactive in Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for WNT7A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein Wnt-7a
NCBI Official Synonym Full Names
Wnt family member 7A
NCBI Official Symbol
WNT7A
UniProt Protein Name
Protein Wnt-7a
UniProt Gene Name
WNT7A
NCBI Protein Information
protein Wnt-7a

NCBI Summary for WNT7A

This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is involved in the development of the anterior-posterior axis in the female reproductive tract, and also plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function. Mutations in this gene are associated with Fuhrmann and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndromes. [provided by RefSeq, Jul 2008]
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UniProt Comments for WNT7A

Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway (). Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development (PubMed:16826533). Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes. Required for normal neural stem cell proliferation in the hippocampus dentate gyrus. Required for normal progress through the cell cycle in neural progenitor cells, for self-renewal of neural stem cells, and for normal neuronal differentiation and maturation. Promotes formation of synapses via its interaction with FZD5 ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-WNT7A antibody

 Reference Product  PubMed Publications
 FZD5 antibody  >10 publications with WNT7A and FZD5
 FZD7 antibody  >9 publications with WNT7A and FZD7
 LRP6 antibody  >8 publications with WNT7A and LRP6
 FZD10 antibody  >8 publications with WNT7A and FZD10
 FZD3 antibody  >7 publications with WNT7A and FZD3
 FZD4 antibody  >6 publications with WNT7A and FZD4
 SFRP1 antibody  >4 publications with WNT7A and SFRP1
 FZD9 antibody  >4 publications with WNT7A and FZD9
 PORCN antibody  >1 publications with WNT7A and PORCN

Pathways associated with anti-WNT7A antibody

 Products by Pathway  Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 DNA Damage Response (only ATM Dependent) Pathway antibodies  DNA Damage Response (only ATM Dependent) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Hedgehog Signaling Pathway antibodies  Hedgehog Signaling Pathway Diagram

Diseases associated with anti-WNT7A antibody

 Disease Name  Pubmed Publications
 Female Urogenital Diseases Antibodies  >29 publications with WNT7A and Female Urogenital Diseases
 Lung Diseases Antibodies  >17 publications with WNT7A and Lung Diseases
 Urogenital Neoplasms Antibodies  >15 publications with WNT7A and Urogenital Neoplasms
 Disease Models, Animal Antibodies  >15 publications with WNT7A and Disease Models, Animal
 Nervous System Diseases Antibodies  >11 publications with WNT7A and Nervous System Diseases
 Death Antibodies  >11 publications with WNT7A and Death
 Uterine Neoplasms Antibodies  >11 publications with WNT7A and Uterine Neoplasms
 Fuhrmann syndrome Antibodies  >10 publications with WNT7A and Fuhrmann syndrome
 Inflammation Antibodies  >9 publications with WNT7A and Inflammation
 Endometrial Neoplasms Antibodies  >8 publications with WNT7A and Endometrial Neoplasms

Organs/Tissues associated with anti-WNT7A antibody

 Organ/Tissue Name  Pubmed Publications
 Uterus Antibodies  >56 publications with WNT7A and Uterus
 Embryonic Tissue Antibodies  >52 publications with WNT7A and Embryonic Tissue
 Brain Antibodies  >52 publications with WNT7A and Brain
 Ovary Antibodies  >6 publications with WNT7A and Ovary
 Prostate Antibodies  >5 publications with WNT7A and Prostate
 Placenta Antibodies  >5 publications with WNT7A and Placenta
 Testis Antibodies  >4 publications with WNT7A and Testis