Artocarpus integrifolia (AIA)
Cat# 518232-10mg
Size : 10mg
Brand : US Biological
Grade
Affinity PurifiedShipping Temp
Blue IceStorage Temp
-20°CAIA
Jacalin lectin (AIA) is purified by affinity chromatography and is tetrameric two-chain structure consisting of four identical protomers with an isoelectric point of pH 7.8. The lectin has specificity for blood group types O (+SA) and T. Jacalin is considered a galactose-specific lectin and elutes with galactose or melibiose. A post-translational proteolytic modification of Jacalin gives the lectin a novel carbohydrate-binding site involving the N terminus of the alpha; -chain. The protein’s structure explains it’s carbohydrate-binding specificity of T-antigen disaccharide Galβ1,3GalNAc. Potent inhibitors of jacalin include D-galactose, β-Met-Gal and 2-deoxy-alpha; -D-galactose.
Source:
Jacalin
Blood Specificity:
O (+SA), T antigen
Sugar Specificity:
Galbeta; 3GalNAc
Inhibitory Carbohydrate:
Galactose or Melibiose
Divalent Ions:
None Required
Storage and Stability:
Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Jacalin
Purity
Affinity purified
Form
Supplied as a lyophilized powder.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.