Target Cell Antibody Binding

Assays that enable the sensitive and reproducible detection of binding events

Target Cell Antibody Binding

Most of the protein-based therapeutics that are used to treat cancer bind to cell surface antigens. Hence, robust assays that enable the sensitive and reproducible detection of these binding events if critical for the assessment of potential cancer therapeutics. At Aragen Bioscience, the binding of this class of test agents (antibodies, peptides, other types of ligands) is generally performed using flow cytometry. This method is very sensitive and has single cell resolution which provides many advantages over alternative techniques. Fluorophore-labeled test agent is bound to the cells and fluorescence measured by FACS.

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