γ-Terpinene synthase

γ-Terpinene synthase (EC 4.2.3.114) requires Mg2+ for optimal activity, with Mn2+ being less effective. The reaction involves a 1,2-hydride shift, resulting in the loss of the 5-pro-S hydrogen from geranyl diphosphate. In addition to γ-terpinene, trace amounts of several other monoterpenes are produced.