Alpha Smooth Muscle Actin Conjugated Antibody
Cat# MBS9455940-0,1mL-AF405
Size : 0.1mL(AF405)
Brand : MyBiosource
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Alpha Smooth Muscle Actin (ACTA2) Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9455940Actins are highly conserved proteins involved in cell motility, structure and integrity. Actin has been found to be expressed in at least six isomeric forms. It is expressed in heart and skeletal striated muscle tissue, and in certain smooth muscle tissues,… More details
Product Overview
Product Name
Alpha Smooth Muscle Actin (ACTA2), Polyclonal Antibody
Full Product Name
Alpha Smooth Muscle Actin Conjugated Antibody
Product Gene Name
anti-ACTA2 antibody
Product Synonym Names
a actin antibody; AAT6 antibody; ACTA_HUMAN antibody; ACTA2 antibody; Actin alpha 2 smooth muscle aorta antibody; Actin aortic smooth muscle antibody; Actin; aortic smooth muscle antibody; ACTSA antibody; ACTVS antibody; Alpha 2 actin antibody; Alpha actin 2 antibody; Alpha cardiac actin antibody; Alpha-actin-2 antibody; Cell growth inhibiting gene 46 protein antibody; Cell growth-inhibiting gene 46 protein antibody; GIG46 antibody; Growth inhibiting gene 46 antibody; MYMY5 antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Predicted to react with Xenopus laevis, Chicken, Cow, Horse, Monkey
Predicted to react with Xenopus laevis, Chicken, Cow, Horse, Monkey
Form/Format
0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
Preparation and Storage
Store at 4 degree C for 6 months.
Applications Tested/Suitable for anti-ACTA2 antibody
Most Applications
Application Notes for anti-ACTA2 antibody
Suggested Dilution:
AF350 conjugated: most applications: 1:50-1:250
AF405 conjugated: most applications: 1:50-1:250
AF488 conjugated: most applications: 1:50-1:250
AF555 conjugated: most applications: 1:50-1:250
AF594 conjugated: most applications: 1:50-1:250
AF647 conjugated: most applications: 1:50-1:250
AF680 conjugated: most applications: 1:50-1:250
AF750 conjugated: most applications: 1:50-1:250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000
AF350 conjugated: most applications: 1:50-1:250
AF405 conjugated: most applications: 1:50-1:250
AF488 conjugated: most applications: 1:50-1:250
AF555 conjugated: most applications: 1:50-1:250
AF594 conjugated: most applications: 1:50-1:250
AF647 conjugated: most applications: 1:50-1:250
AF680 conjugated: most applications: 1:50-1:250
AF750 conjugated: most applications: 1:50-1:250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000
Other Notes
Small volumes of anti-ACTA2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for ACTA2 purchase
MBS9455940 is an antibody targeting ACTA2. Also known as Alpha Smooth Muscle Actin Conjugated Antibody. Reactive in Human, Mouse, Rat
Predicted to react with Xenopus laevis, Chicken, Cow, Horse, Monkey. Host: Rabbit.
Predicted to react with Xenopus laevis, Chicken, Cow, Horse, Monkey. Host: Rabbit.
Additional Details
NCBI/Uniprot data below describe general gene information for ACTA2. It may not necessarily be applicable to this product.
NCBI Official Full Name
actin, alpha 2, smooth muscle, aorta, isoform CRA_a
NCBI Official Synonym Full Names
actin, alpha 2, smooth muscle, aorta
NCBI Official Symbol
ACTA2
NCBI Official Synonym Symbols
AAT6; ACTSA; MYMY5
UniProt Protein Name
Actin, aortic smooth muscle
UniProt Synonym Protein Names
Alpha-actin-2; Cell growth-inhibiting gene 46 protein
Protein Family
Actin
UniProt Gene Name
ACTA2
UniProt Synonym Gene Names
ACTSA; ACTVS
UniProt Entry Name
ACTA_HUMAN
NCBI Protein Information
actin, aortic smooth muscle; alpha-cardiac actin; cell growth-inhibiting gene 46 protein
NCBI Summary for ACTA2
The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008]
Show more UniProt Comments for ACTA2
ACTA2: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Up-regulated in response to enterovirus 71 (EV71) infection. Belongs to the actin family.
Protein type: Contractile; Motility/polarity/chemotaxis; Cytoskeletal
Chromosomal Location of Human Ortholog: 10q23.3
Cellular Component: extracellular space; smooth muscle contractile fiber; protein complex; cytoplasm; cytosol; actin cytoskeleton
Molecular Function: protein kinase binding; ATP binding
Biological Process: muscle contraction; regulation of blood pressure; response to virus; vascular smooth muscle contraction
Disease: Moyamoya Disease 5; Multisystemic Smooth Muscle Dysfunction Syndrome; Aortic Aneurysm, Familial Thoracic 6
Show more Protein type: Contractile; Motility/polarity/chemotaxis; Cytoskeletal
Chromosomal Location of Human Ortholog: 10q23.3
Cellular Component: extracellular space; smooth muscle contractile fiber; protein complex; cytoplasm; cytosol; actin cytoskeleton
Molecular Function: protein kinase binding; ATP binding
Biological Process: muscle contraction; regulation of blood pressure; response to virus; vascular smooth muscle contraction
Disease: Moyamoya Disease 5; Multisystemic Smooth Muscle Dysfunction Syndrome; Aortic Aneurysm, Familial Thoracic 6
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-ACTA2 antibody
| Reference Product | PubMed Publications |
|---|---|
| TGFB1 antibody | >141 publications with ACTA2 and TGFB1 |
| MYH11 antibody | >26 publications with ACTA2 and MYH11 |
| TAGLN antibody | >10 publications with ACTA2 and TAGLN |
| CFL1 antibody | >1 publications with ACTA2 and CFL1 |
| UBC antibody | >1 publications with ACTA2 and UBC |
| ACTN2 antibody | >1 publications with ACTA2 and ACTN2 |
Pathways associated with anti-ACTA2 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Muscle Contraction Pathway antibodies | Muscle Contraction Pathway Diagram |
| Myometrial Relaxation And Contraction Pathways antibodies | Myometrial Relaxation And Contraction Pathways Diagram |
| Smooth Muscle Contraction Pathway antibodies | Smooth Muscle Contraction Pathway Diagram |
| Striated Muscle Contraction Pathway antibodies | Striated Muscle Contraction Pathway Diagram |
| Vascular Smooth Muscle Contraction Pathway antibodies | Vascular Smooth Muscle Contraction Pathway Diagram |
| Vascular Smooth Muscle Contraction Pathway antibodies | Vascular Smooth Muscle Contraction Pathway Diagram |
Diseases associated with anti-ACTA2 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Neoplasms Antibodies | >222 publications with ACTA2 and Neoplasms |
| Fibrosis Antibodies | >217 publications with ACTA2 and Fibrosis |
| Inflammation Antibodies | >66 publications with ACTA2 and Inflammation |
| Liver Diseases Antibodies | >65 publications with ACTA2 and Liver Diseases |
| Disease Models, Animal Antibodies | >57 publications with ACTA2 and Disease Models, Animal |
| Liver Cirrhosis Antibodies | >48 publications with ACTA2 and Liver Cirrhosis |
| Kidney Diseases Antibodies | >41 publications with ACTA2 and Kidney Diseases |
| Breast Neoplasms Antibodies | >33 publications with ACTA2 and Breast Neoplasms |
| Aortic Aneurysm, Thoracic Antibodies | >29 publications with ACTA2 and Aortic Aneurysm, Thoracic |
| Heart Diseases Antibodies | >27 publications with ACTA2 and Heart Diseases |
Organs/Tissues associated with anti-ACTA2 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Muscle Antibodies | >569 publications with ACTA2 and Muscle |
| Vascular Antibodies | >173 publications with ACTA2 and Vascular |
| Blood Antibodies | >126 publications with ACTA2 and Blood |
| Eye Antibodies | >99 publications with ACTA2 and Eye |
| Lung Antibodies | >99 publications with ACTA2 and Lung |
| Connective Tissue Antibodies | >89 publications with ACTA2 and Connective Tissue |
| Liver Antibodies | >85 publications with ACTA2 and Liver |
| Kidney Antibodies | >71 publications with ACTA2 and Kidney |
| Skin Antibodies | >63 publications with ACTA2 and Skin |
| Embryonic Tissue Antibodies | >47 publications with ACTA2 and Embryonic Tissue |