Anti-Phospho-CAMKII alpha/gamma (Thr286) Polyclonal Antibody

Application

ELISA

ICC/IF

IHC-P

WB

Recommended DoseAntibody TypeHost SpeciesRabbitConstructionPolyclonal AntibodyPurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.AppearanceLiquidFormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Research Backgroundcalcium/calmodulin dependent protein kinase II alpha(CAMK2A) Homo sapiens The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008], Related Conjugates and Formulations

Conjucates	Unconjugated
Others Formats	Phospho

Antigen Details

Immunogen	A synthesized phosphopeptide: human CaMK2 around the phosphorylation site of Thr286. AA range:256-305
Antigen Species	Human
Uniprot ID	Q9UQM7 & Q13555

Chemical Properties

Molecular Weight

Actual: 54 kDa.

Stability & Storage

Stability & Storage	Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
Transport	Shipping with blue ice.