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Reagents and instruments for immunology, cell biology and molecular biology.

Dansyl glutathione [75017-02-6]

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Cat# NB-64-02195-10mg

Size : 10mg

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Phone : +1 850 650 7790

Brand : Neo Biotech

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Phone : +1 850 650 7790

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Dansyl glutathione

(Synonyms: DNS-glutathione) Copy Product Info

Synonyms: DNS-glutathione

Catalog No. T10956 Copy Product Info

Purity: 99.70%

Dansyl glutathione is a fluorescent trapping agent and a dansyl-labeled glutathione derivative. it enhances LC-MS/MS sensitivity for reactive metabolite identification in toxicity screening.

Cas No. 75017-02-6

For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.70%

ee:100%

Appearance:Solid

Color:Yellow

Product Introduction

Bioactivity

Description	Dansyl glutathione is a fluorescent trapping agent and a dansyl-labeled glutathione derivative. it enhances LC-MS/MS sensitivity for reactive metabolite identification in toxicity screening.
In vitro	Dansyl glutathione acts as a robust nucleophile in human liver microsomes to trap transient electrophilic metabolites generated by CYP450 [1].
Synonyms	DNS-glutathione

Chemical Properties

Molecular Weight	540.61
Formula	C₂₂H₂₈N₄O₈S₂
Cas No.	75017-02-6
Smiles	S(N[C@@H](CCC(N[C@H](C(NCC(O)=O)=O)CS)=O)C(O)=O)(=O)(=O)C=1C2=C(C(N(C)C)=CC=C2)C=CC1
Relative Density.	1.435 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (147.98 mM), Sonication is recommmended.

H2O: 40 mg/mL (73.99 mM), Sonication is recommmended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	1.8498 mL	9.2488 mL	18.4976 mL	92.4881 mL
5 mM	0.3700 mL	1.8498 mL	3.6995 mL	18.4976 mL
10 mM	0.1850 mL	0.9249 mL	1.8498 mL	9.2488 mL
20 mM	0.0925 mL	0.4624 mL	0.9249 mL	4.6244 mL
50 mM	0.0370 mL	0.1850 mL	0.3700 mL	1.8498 mL

DMSO

	1mg	5mg	10mg	50mg
100 mM	0.0185 mL	0.0925 mL	0.1850 mL	0.9249 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

Keywords

Dansyl glutathione

Related Tags: Dansyl glutathione chemical structure | Dansyl glutathione in vitro | Dansyl glutathione formula | Dansyl glutathione molecular weight