Digitonin is a naturally occurring surfactant especially useful for receptor solubilization. The detergent is frequently applied as hemolysis reagent and for permeabilization of certain types of cells e.g. blood platelets, hepatocytes, yeast or tumor cells. Also used for the estimation of cholesterol.
CMC (25 °C) 0.67 - 0.73 mM, Na (25 °C) 60, HLB 0.4


References:

1. Scallen, D.J. & Dietert, S.E. (1969) J. Cell Biol. 40, 802- 13
2. Grigoriadis, D.E. et al. (1989) Endocrinology 125, 3068-77
3. Hermann, P. et al. (1988) Photosynthetica 22, 411-22
4. Boschmann, M. et al. (1989) Biomed. Biochim. Acta 48, 645-52
5. Mooney, R.A. (1988) in Meth. Enzymol. 159, (Corbin, J.D. & Johnson, R.A., Eds.) 193-202, Academic Press, Inc.

DANGER

Hazard Statements	H301 - H311 - H331
Precautions	P280
Reaction	P301 +P310 - P302 +P352 - P304 +P340 - P311 - P330

GGVSE/ADR: 6.1 II UN2811 • IATA: 6.1 II UN2811 • EINECS: 234-255-6 • WGK: 3L • HS: 29389010
Storage Temperature: +15 °C to +30 °C