DMG-PEG 2000 [160743-62-4]
Cat# T9098-200mg
Size : 200mg
Brand : TargetMol
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Phone : +1 850 650 7790
DMG-PEG 2000
(Synonyms: DMG-PEG2000) Copy Product InfoDMG-PEG 2000 (DMG-PEG2000) can be used for the preparation of lipid nanoparticles for the in vivo delivery of plasmid DNA via oral administration, enhancing the mucosal permeability and delivery efficiency of the nanoparticles. DMG-PEG 2000 can be used for the preparation of liposomes for siRNA transfection, improving transfection efficiency.
Cas No. 160743-62-4
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:≥98%
Appearance:Solid
Color:White
COA HNMR
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | DMG-PEG 2000 (DMG-PEG2000) can be used for the preparation of lipid nanoparticles for the in vivo delivery of plasmid DNA via oral administration, enhancing the mucosal permeability and delivery efficiency of the nanoparticles. DMG-PEG 2000 can be used for the preparation of liposomes for siRNA transfection, improving transfection efficiency. |
| In vivo | METHODS: To study the permeability of NP-3, a single dose of NP-3 (150 μg DNA per mouse) was administered orally to mice. RESULTS: The NP-3 group maintained high luciferase expression in the liver, lung, and intestinal regions within 12 to 24 hours after administration. In addition, NP-3 showed a 1.5-fold higher signal intensity than the NP-1 or NP-2 groups within 12 to 24 hours after oral administration. [1] |
| Synonyms | DMG-PEG2000 |
| Molecular Weight | 2526 |
| Formula | (C2H4O)nC32H62O5 |
| Cas No. | 160743-62-4 |
| Smiles | N.CCCCCCCCCCCCCC(=O)OCC(COCCOC)OC(=O)CCCCCCCCCCCCC |
| Relative Density. | no data available |
| Storage | Store at low temperature,Keep away from direct sunlight,Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||
| Solubility Information | Ethanol: 100 mg/mL (39.59 mM), Sonication is recommended.  DMSO: 60 mg/mL (23.75 mM), Sonication is recommended. | |||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (0.79 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO/Ethanol
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | ||||||||||||||||||||||||||