HUMAN Transforming Growth Factor beta 1 - (h-TGF-beta)

Cat# 100-39-5UG

Size : 5ug

Brand : Shenandoah

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Phone : +1 850 650 7790

Recombinant Human TGF-β 1

Catalog ID
100-39
Size
5 µg 100-39-5UG
20 µg 100-39-20UG
100 µg 100-39-100UG
500 µg 100-39-500UG
Details

Transforming growth factor-beta 1 (TGF-β 1) is a member of the TGF-beta superfamily of cytokines. Members of this family exhibit regulatory activity in immunity, proliferation, adhesion, migration, and growth inhibition pathways. TGF-β 1signals through SMAD proteins via the TGF-βRI and TGF-βRII receptors.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names Differentiation inhibiting factor, cartilage-inducing factor
Accession Number P01137
Source Genetically modified CHO cells
Predicted Molecular Mass Dimer, 12.8/25.6 kDa (112/224 aa)
AA Sequence ALDTNYCFSS TEKNCCVRQL YIDFRKDLGW KWIHEPKGYH ANFCLGPCPY IWSLDTQYSK VLALYNQHNP GASAAPCCVP QALEPLPIVY YVGRKPKVEQ LSNMIVRSCK CS
Formulation Lyophilized from a 0.2 µm filtered solution containing 0.1 % trifluoroacetic acid (TFA) and Trehalose in a 20:1 Trehalose to protein ratio
Product Reconstitution Sterile 10 mM HCl at 0.1 mg/mL
Country of Origin USA

 

Specification* Method of Determination Acceptance Criteria
Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
Endotoxin Kinetic LAL ≤ 0.1 EU/µg
Biological Activity (ED50) Inhibition of IL-4-induced HT-2 cell proliferation ≤ 0.5 ng/mL

 

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements. 

TGF beta TGF-beta

Specifications

Storage
At or below -20°C
Shelf Life
12 months from date of receipt when stored at -20°C to -80°C as supplied.

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