IL-34 Protein, Human, Recombinant (His)
Cat# TMPY-05296-10ug
Size : 10ug
Brand : TargetMol
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IL-34 Protein, Human, Recombinant (His)
(Synonyms: interleukin 34, IL-34, C16orf77) Copy Product InfoIL-34 Protein, Human, Recombinant (His) is expressed in CHO mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession number is AAH29804.1.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:96.7%
Appearance:Lyophilized powder
Color:White
COAUser Guide of Recombinant Proteins
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Measured in a cell proliferation assay using human peripheral blood mononuclear cell. The ED50 for this effect is 2-8 ng/mL. |
| Description | IL-34 Protein, Human, Recombinant (His) is expressed in CHO mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession number is AAH29804.1. |
| Species | Human |
| Expression System | CHO Cells |
| Tag | C-His |
| Accession Number | AAH29804.1 |
| Construction | A DNA sequence encoding the human IL34 (AAH29804.1) (Met1-Pro242) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Asn 21 |
| Protein Purity | > 95 % as determined by SDS-PAGE.  |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot. |
| Synonyms | interleukin 34, IL-34, C16orf77 |
| Research Background | IL34 (Interleukin 34) is a Protein Coding gene. IL-34, also known as uncharacterized protein C16 or f77 homolog, belongs to the IL-34 family. IL-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R). IL-34 protein is expressed in various tissues, including heart, brain, lung, liver, kidney, spleen, thymus, testes, ovary, small intestine, prostate, and colon, and most abundant in the spleen. The colony-stimulating factor 1 receptor (CSF-1R) is identified as the receptor for IL-34. IL-34 increases the growth or survival of immune cells known as monocytes. Besides, IL-34 promoted the formation of the colony-forming unit-macrophage (CFU-M), a macrophage progenitor, in human bone marrow cultures. |
| Molecular Weight | 26.7 kDa (predicted) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |