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> IZUMO1 Protein, Human, Recombinant (His & Myc)

IZUMO1 Protein, Human, Recombinant (His & Myc)

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Cat# NB-64-50243-1mg

Size : 1mg

Brand : Neo Biotech

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IZUMO1 Protein, Human, Recombinant (His & Myc)

(Synonyms: Sperm-specific protein izumo, Oocyte binding/fusion factor (OBF), IZUMO1, Izumo sperm-egg fusion protein 1) Copy Product Info

Synonyms: Sperm-specific protein izumo, Oocyte binding/fusion factor (OBF), IZUMO1, Izumo sperm-egg fusion protein 1

Catalog No. TMPH-01567 Copy Product Info
Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'.
Other Forms of IZUMO1 Protein, Human, Recombinant (His & Myc):
IZUMO1 Protein, Human, Recombinant (His)TMPY-03220
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For research use only—not for human use. No sales to individuals. Use as intended only.

Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'.
Species
Human
Expression System
E. coli
TagN-10xHis, C-Myc
Accession NumberQ8IYV9
Amino AcidCVICDPSVVLALKSLEKDYLPGHLDAKHHKAMMERVENAVKDFQELSLNEDAYMGVVDEATLQKGSWSLLKDLKRITDSDVKGDLFVKELFWMLHLQKETFATYVARFQKEAYCPNKCGVMLQTLIWCKNCKKEVHACRKSYDCGERNVEVPQMEDMILDCELNWHQASEGLTDYSFYRVWGNNTETLVSKGKEATLTKPMVGPEDAGSYRCELGSVNSSPATIINFHVTVLPKMIKEEKPSPNIVTPGEATTESSISLQPLQPEKMLASR
Construction22-292 aa
Protein Purity
> 85% as determined by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
ReconstitutionReconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsSperm-specific protein izumo, Oocyte binding/fusion factor (OBF), IZUMO1, Izumo sperm-egg fusion protein 1
Research Background
Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'.
Chemical Properties
Molecular Weight38.1 kDa (predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

OBFIZUMO 1
Related Tags: IZUMO1 Protein, Human, Recombinant (His & Myc) chemical structure | IZUMO1 Protein, Human, Recombinant (His & Myc) molecular weight