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> n-Dodecyl-beta-D-maltoside (DDM) [69227-93-6]

n-Dodecyl-beta-D-maltoside (DDM) [69227-93-6]

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Cat# 207281-1g

Size : 1g

Brand : US Biological

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Phone : +1 850 650 7790

207281 n-Dodecyl-beta-D-maltoside (DDM)

Grade
Highly Purified
Shipping Temp
Blue Ice
Storage Temp
-20°C

Non-ionic detergent. For functional solubilization, purification and crystallography of membrane proteins. For the stabilization and activation of enzymes.

Synonyms:
1-Dodecyl-β-D-maltoside; DDM; DDM (Detergent); Dodecyl O-β-D-Maltoside; Dodecyl β-D-Maltopyranoside; Dodecyl β-D-Maltoside; Dodecyl β-Maltopyranoside; Dodecyl β-Maltoside; Lauryl Maltoside; Lauryl β-D-Maltopyranoside; Lauryl β-D-Maltoside; Lauryl β-Maltopyranoside; Lauryl β-Maltoside; n-Dodecyl β-D-Maltopyranoside; β-1-n-Dodecyl-D-Maltoside; (2R,3R,4S,5S,6R)-2-(((2R,3S,4R,5R,6S)-6-(Dodecyloxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-trio

CAS No:
69227-93-6

Molecular Formula:
C24H46O11

Molecular Weight:
510.62

Purity (HPLC):
≥95%

Appearance:
White powder

Optical Rotation:
+45 to +49°

Solubility:
Ethanol and DMSO: 10mg/ml
DMF: 20mg/ml

Method of Determining Identity:
Proton NMR and Mass Spectrometric Analysis

Storage and Stability:
Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with ethanol, DMSO or DMF. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Applications
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. ||Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
References
1. Synthesis and properties of some alpha-D-alkyl glucosides and mannosides: apparent molal volumes and solubilization of nitrobenzene in water at 25°C: G.M. Brown, et al.; Can. J. Chem. 48: 2525 (1970). 2. Detergent-mediated reconstitution of membrane proteins: J. Knol, et al.; Biochem. 37: 16410 (1998). 3. Macromolecular Crystallography Protocols: S. Doublie; Methods Mol. Biol. 363: (2007). 4. The use of detergents to purify membrane proteins; T. Arnold & D. Linke; Curr. Protoc. Protein Sci. Chapter 4: Unit 4.8.1-4.8.30 (2008). 5. Expression, purification and in vitro functional reconstitution of the chemokine receptor CCR1: S.J. Allen, et al.; Prot. Expr. Purif. 66: 73 (2009). 6. Structuring detergents for extracting and stabilizing functional membrane proteins: R. Matar-Merheb, et al.; PLoS One 6: e18036 (2011). 7. Efficiency of detergents at maintaining membrane protein structures in their biologically relevant forms: D.V. Tulumello & C.M. Deber; Biochim. Biophys. Acta. 1818: 1351 (2012)