Recombinant Human CXCL1 Protein
Cat# MBS8248895-0,05mg
Size : 0.05mg
Brand : MyBiosource
Contact local distributor :
Phone : +1 850 650 7790
CXCL1 Human Recombinant Protein
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8248895Recombinant Human CXCL1 Protein is produced by our Mammalian expression system and the target gene encoding Ala35-Asn107 is expressed with a 6His tag at the C-terminus. More details
Product Overview
Online Datasheet in PDFProduct Name
CXCL1, Recombinant Protein
Full Product Name
Recombinant Human CXCL1 Protein
Product Gene Name
CXCL1 recombinant protein
Product Synonym Names
GRO; GRO1; GROA; MGSA; SCYB1; Growth-regulated alpha protein; C-X-C motif chemokine 1; GRO-alpha(1-73); Melanoma growth stimulatory activity; MGSA; Neutrophil-activating protein 3; NAP-3
Sequence
ASVATELRCQ CLQTLQGIHP KNIQSVNVKS PGPHCAQTEV IATLKNGRKA CLNPASPIVK KIIEKMLNSD KSNVDHHHHH H
Host
Human cells
Species Reactivity
Human
Form/Format
Lyophilized from a 0.2 uM filtered solution of 20mM PB, 150mM NaCl, 5% Trehalose, pH 7.4
Purity/Purification
Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
Preparation and Storage
Lyophilized protein should be stored at -20 degree C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 2-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at -20 degree C for 3 months.
OMIM
J03561 mRNA
Endotoxin
Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Directions for Use
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Applications Tested/Suitable for CXCL1 recombinant protein
ELISA (EIA), Western Blot (WB), SDS-PAGE (SDS), Mass Spectrometry (MS)
Other Notes
Small volumes of CXCL1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for CXCL1 purchase
MBS8248895 is a recombinant protein targeting CXCL1. Also known as Recombinant Human CXCL1 Protein. Reactive in Human. Host: Human cells.
Additional Details
NCBI/Uniprot data below describe general gene information for CXCL1. It may not necessarily be applicable to this product.
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
growth-regulated alpha protein
NCBI Official Synonym Full Names
C-X-C motif chemokine ligand 1
NCBI Official Symbol
CXCL1
NCBI Official Synonym Symbols
FSP; GRO1; GROa; MGSA; NAP-3; SCYB1; MGSA-a
UniProt Protein Name
Growth-regulated alpha protein
UniProt Synonym Protein Names
C-X-C motif chemokine 1; GRO-alpha(1-73); Melanoma growth stimulatory activity; MGSA
Protein Family
Growth-regulated alpha protein
UniProt Gene Name
CXCL1
UniProt Synonym Gene Names
GRO; GRO1; GROA; MGSA; SCYB1; MGSA; NAP-3
UniProt Entry Name
GROA_HUMAN
NCBI Protein Information
growth-regulated alpha protein
NCBI Summary for CXCL1
This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014]
Show more UniProt Comments for CXCL1
CXCL1: Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO- alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity. Belongs to the intercrine alpha (chemokine CxC) family.
Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 4q21
Cellular Component: extracellular region
Molecular Function: CXCR chemokine receptor binding; enzyme activator activity; receptor binding
Biological Process: actin cytoskeleton organization and biogenesis; cell proliferation; chemotaxis; G-protein coupled receptor protein signaling pathway; immune response; negative regulation of cell proliferation; nervous system development; response to lipopolysaccharide; signal transduction
Show more Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 4q21
Cellular Component: extracellular region
Molecular Function: CXCR chemokine receptor binding; enzyme activator activity; receptor binding
Biological Process: actin cytoskeleton organization and biogenesis; cell proliferation; chemotaxis; G-protein coupled receptor protein signaling pathway; immune response; negative regulation of cell proliferation; nervous system development; response to lipopolysaccharide; signal transduction
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with CXCL1 recombinant protein
| Reference Product | PubMed Publications |
|---|---|
| CXCR2 recombinant protein | >393 publications with CXCL1 and CXCR2 |
| CCL5 recombinant protein | >297 publications with CXCL1 and CCL5 |
| CXCL10 recombinant protein | >260 publications with CXCL1 and CXCL10 |
| CCL20 recombinant protein | >128 publications with CXCL1 and CCL20 |
| CXCR1 recombinant protein | >123 publications with CXCL1 and CXCR1 |
| CXCL12 recombinant protein | >103 publications with CXCL1 and CXCL12 |
| CXCL11 recombinant protein | >40 publications with CXCL1 and CXCL11 |
| CCR1 recombinant protein | >37 publications with CXCL1 and CCR1 |
| CCR5 recombinant protein | >36 publications with CXCL1 and CCR5 |
| CXCR3 recombinant protein | >36 publications with CXCL1 and CXCR3 |
Pathways associated with CXCL1 recombinant protein
| Products by Pathway | Pathway Diagram |
|---|---|
| Amoebiasis Pathway antibodies | Amoebiasis Pathway Diagram |
| Amoebiasis Pathway antibodies | Amoebiasis Pathway Diagram |
| Chemokine Receptors Bind Chemokines Pathway antibodies | Chemokine Receptors Bind Chemokines Pathway Diagram |
| Chemokine Signaling Pathway antibodies | Chemokine Signaling Pathway Diagram |
| Chemokine Signaling Pathway antibodies | Chemokine Signaling Pathway Diagram |
| Class A/1 (Rhodopsin-like Receptors) Pathway antibodies | Class A/1 (Rhodopsin-like Receptors) Pathway Diagram |
| Cytokine Signaling In Immune System Pathway antibodies | Cytokine Signaling In Immune System Pathway Diagram |
| Cytokine-cytokine Receptor Interaction Pathway antibodies | Cytokine-cytokine Receptor Interaction Pathway Diagram |
| Cytokine-cytokine Receptor Interaction Pathway antibodies | Cytokine-cytokine Receptor Interaction Pathway Diagram |
| Cytokines And Inflammatory Response Pathway antibodies | Cytokines And Inflammatory Response Pathway Diagram |
Diseases associated with CXCL1 recombinant protein
| Disease Name | Pubmed Publications |
|---|---|
| Inflammation Antibodies | >1501 publications with CXCL1 and Inflammation |
| Necrosis Antibodies | >683 publications with CXCL1 and Necrosis |
| Disease Models, Animal Antibodies | >554 publications with CXCL1 and Disease Models, Animal |
| Lung Diseases Antibodies | >421 publications with CXCL1 and Lung Diseases |
| Cardiovascular Diseases Antibodies | >245 publications with CXCL1 and Cardiovascular Diseases |
| Lung Injury Antibodies | >203 publications with CXCL1 and Lung Injury |
| Pneumonia Antibodies | >151 publications with CXCL1 and Pneumonia |
| Fibrosis Antibodies | >126 publications with CXCL1 and Fibrosis |
| Wounds and Injuries Antibodies | >114 publications with CXCL1 and Wounds and Injuries |
| Reperfusion Injury Antibodies | >114 publications with CXCL1 and Reperfusion Injury |
Organs/Tissues associated with CXCL1 recombinant protein
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >1513 publications with CXCL1 and Blood |
| Lung Antibodies | >619 publications with CXCL1 and Lung |
| Vascular Antibodies | >450 publications with CXCL1 and Vascular |
| Liver Antibodies | >244 publications with CXCL1 and Liver |
| Skin Antibodies | >216 publications with CXCL1 and Skin |
| Intestine Antibodies | >193 publications with CXCL1 and Intestine |
| Heart Antibodies | >108 publications with CXCL1 and Heart |
| Connective Tissue Antibodies | >80 publications with CXCL1 and Connective Tissue |
| Uterus Antibodies | >36 publications with CXCL1 and Uterus |
| Ascites Antibodies | >6 publications with CXCL1 and Ascites |