Sterigmatocystine [10048-13-2]
Cat# T16942-1mg
Size : 1mg
Brand : TargetMol
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Sterigmatocystine
Copy Product InfoSterigmatocystine is an inhibitor of G1 Phase and DNA synthesis and is used to inhibit p21 activity. Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor.
Cas No. 10048-13-2
For research use only—not for human use. No sales to individuals. Use as intended only.
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Sterigmatocystine is an inhibitor of G1 Phase and DNA synthesis and is used to inhibit p21 activity. Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor. |
| In vitro | Sterigmatocystine-induced DNA damage activates the ATM/53-dependent signaling pathway, leading to G2 arrest in GES-1 cells [4]. |
| In vivo | Sterigmatocystine (ip; 3 mg/kg once daily for 14 days) suppresses p21WAF1/CIP1 [3]. |
| Molecular Weight | 324.28 |
| Formula | C18H12O6 |
| Cas No. | 10048-13-2 |
| Smiles | 14[C@]12OC=C[C@@]1(14)c1c(O2)cc(OC)c2c1oc1cccc(O)c1c2=O |
| Relative Density. | 1.51 g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |