Reagents and instruments for immunology, cell biology and molecular biology.
 
> thymol [89-83-8]

thymol [89-83-8]

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Cat# orb1223718-1g

Size : 1g

Brand : Biorbyt

Contact local distributor :


Phone : +1 850 650 7790

thymol

SKU: orb1223718

Description

Thymol is a dye that is also known as 5-Methyl-2-(1-methylethyl)phenol.

Research Area

Pharmacology & Drug Discovery

Images & Validation

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thymol

Key Properties

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CAS Number89-83-8
MW150.22
Purity>98% (HPLC)
FormulaC10H14O
SMILESOC1=CC(C)=CC=C1C(C)C

Bioactivity

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In Vivo
Animal model: orthotopic mouse LUAD model. Dosage: 75 mg/kg for Thymol, 10 mg/kg for anti‐PD‐1 antibody. Administration: anti‐PD‐1 antibody: i.p. , every 1 week from day 5 after tumor injection. Thymol: i.p. , every 2 days from day 5 after tumor injection. Result: Inhibited the progression of LUAD, and increased the survival of mice. Decreases IL4I1 level in tumors. Improved the efficacy of anti‐PD‐1 antibody.
In Vitro
Western blot analysis. Cell line: A549 cells. Concentration: 20 μM. Incubation time: 48 h. Result: Inhibited the protein levels of IL4I1, and the nuclear translocation of AHR.

Storage & Handling

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StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

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Thymol | NSC 11215 | NSC-11215 | NSC11215
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Protocol Information