Preserve & transport fresh cells, tissues & blood, without cryopreservation
The Core Technology: Permeable Alginate Hydrogel Encapsulation
Atelerix products are based on sterile, xeno-free alginate (plant-derived polysaccharide) that forms a thin, highly permeable hydrogels in seconds at room temperature. Cells, viruses, or tissues are gently mixed with the alginate solution and dispensed into vials, plates, or bags where rapid gelation occurs upon contact with calcium ions. The resulting matrix:
Mechanism of Preservation
- Immobilisation prevents sedimentation, aggregation, and shear stress
- High permeability allows O₂/CO₂ and nutrient/waste diffusion
- Hypothermic storage (4–25 °C) reduces metabolic rate by 5–10×
- No cryoprotectants required – eliminates DMSO toxicity
Key Performance Advantages
- Viability typically >90 % after 7–14 days (cell-dependent)
- Full retention of phenotype (surface markers, stemness)
- Preserved functionality in potency assays, differentiation, infectivity
- Viral vectors maintain titre; live viruses remain infectious
- Up to 80 % reduction in transport carbon footprint
Product Portfolio & Scientific Highlights
CytoStor™ – Cells & Viruses
Includes gelBASE beads, non-crosslinked gel and dissolution buffer for the in situ encapsulation, storage and release of cells, viruses, viral vectors and mRNA-LNPs.
Available in small and large kit sizes for storage of up to 10 million cells or 50 million cells per vial, respectively.
Key data:- HepG2 cells: >95 % viability after 8 days at room temp
- Lentivirus: no significant titre loss after 7 days at 20 °C
- AAV vectors: stable transduction efficiency after 14 days hypothermic storage
- mRNA-LNPs preserved without aggregation
LeukoStor™ – Leukapheresis Material
Includes gelBASE beads, non-crosslinked gel and dissolution buffer for the in situ encapsulation, storage and release of leukapheresis material in vials or bags.
Designed for apheresis volumes of 10mL, 30mL and 70mL. Larger volumes are available upon request.
Key data:- Up to 5 days storage at 2–25 °C
- Up to 2× higher viable T-cell yield post-thaw recovery vs standard methods
- Reduced variability in CAR-T manufacturing yield
- Preserved CD4/CD8 ratio and T-cell functionality
WellReady™ – In-Plate Preservation
Includes gelBASE beads, non-crosslinked gel and dissolution buffer for the in situ encapsulation, storage and release of leukapheresis material in vials or bags.
Designed for apheresis volumes of 10mL, 30mL and 70mL. Larger volumes are available upon request.
Key data:- Morphology and confluency maintained for 14 days
- Full metabolic activity and response to stimuli post-recovery
- Ideal for assay-ready plate shipping and functional screening
BeadReady™ – Cell Bead Encapsulation
Includes non-crosslinked gels, gelation buffers and dissolution buffer for the encapsulation, storage and release of cells in suspension.
Key data:
- Up to 50 × 10⁶ cells/vial
- 14-day storage with >90 % recovery
- Beads compatible with 3D printing and high-throughput analysis
TissueReady™ & TissueReady™ Plus
Preservation of biopsies, organoids, spheroids, and microtissues.
Key data:- 5× extension of fresh tissue viability
- Organoids retain structure, proliferation capacity, and differentiation potential
- Ideal for clinical sample collection in remote locations
BloodReady™ – Whole Blood Preservation
Enables the preservation and transport of whole blood at refrigerated temperatures while maintaining immune cell viability and function.
Key data:- Up to 72 h with preserved leukocyte populations
- Surface markers stable for flow cytometry
- No need for immediate processing
Selected References & Resources
Ready to eliminate cryopreservation from your workflow?
Contact our scientific team for protocols, samples, or quotations