VTI1B Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommended Dilution	WB: 1 - 2 ug/mL
Reactivities	Human, Mouse, Rat
Host	Rabbit
Isotype	IgG
Clonality	Polyclonal
Immunogen	VTI1b antibody was raised against a 17 amino acid peptide near the center of human VTI1b.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	VTI1b antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage	Store at -20°C as received.
Stability	Stable for 12 months from date of receipt.
Predicted Protein Size	Predicted: 14, 19, 26 kDa; Observed: 27 kDa
Gene Name	vesicle transport through interaction with t-SNAREs 1B
Database Link	NP_006361 Entrez Gene 10490 Human UniProt ID Q9UEU0
Background	Vesicle transport through interaction with t-SNAREs homolog 1 (VTI1a and VTI1b) are involved in vesicular transport from the late endosomes to the trans-Golgi network (1). They are both localized in the trans-Golgi network, with VTI1a also found in the Golgi apparatus and VTI1b in endosomes (2,3). It is thought that VTI1b along with the SNARE protein VAMP8 mediates the fusion of antimicrobial and canonical autophagosomes with lysosomes, an essential process for autophagy (4).
Synonyms	CARD4; CLR7.1; NLRC1
Reference Data