Maclura pomifera Lectin (MPL/MPA) - Pure
Référence 21510084-1
Conditionnement : 5mg
Marque : BioWorld
Description
Maclura pomifera agglutinin or lectin (MPA/MPL) is tetrameric plant protein purified by affinity chromatography. MPA has a molecular weight of about 44,000 and consists of four subunits. It has an isoelectric point between pH 4.8 and pH 5.3, and blood group specificity towards A, B, and O (-SA). This lectin has a high affinity for tumor-associated T-antigen disaccharide (Gal?1,3GalNAc?) and many O-linked glycopeptide structures. The structure of Gal?1,3GalNAc? occurs on the surface of tumor cells as a mucin-associated antigenic marker, termed as T-antigen. It is also the central element in O-linked glycopeptide structures on other mammalian glycoproteins.
Properties
Shelf life
2 years
Storage Temperature
-20°C
ECCN #
EAR99
Hazmat Ship
Non-Hazardous
Purity
Affinity purified
Appearance form
Lyophilized Powder
Molecular Weight
44 kDa
Solubility (@ RT)
Soluble in PBS
Abbreviation (Lectins Only):
MPL/MPA
Source
Osage orange
Blood Group Specificity
A, B, O (-SA)
Carbohydrate Specificity
Galβ3GalNAc
Conjugate/Tag/Matrix
None
Inhibitory Carbohydrate
Galactose
Divalent Ions
None Required
Mitogenic Activity
Yes