Maclura pomifera Lectin (MPL/MPA) - Pure

Référence 21510084-1

Conditionnement : 5mg

Marque : BioWorld

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Description

Maclura pomifera agglutinin or lectin (MPA/MPL) is tetrameric plant protein purified by affinity chromatography. MPA has a molecular weight of about 44,000 and consists of four subunits. It has an isoelectric point between pH 4.8 and pH 5.3, and blood group specificity towards A, B, and O (-SA). This lectin has a high affinity for tumor-associated T-antigen disaccharide (Gal?1,3GalNAc?) and many O-linked glycopeptide structures. The structure of Gal?1,3GalNAc? occurs on the surface of tumor cells as a mucin-associated antigenic marker, termed as T-antigen. It is also the central element in O-linked glycopeptide structures on other mammalian glycoproteins.

Properties

Shelf life

2 years

Storage Temperature

-20°C

ECCN #

EAR99

Hazmat Ship

Non-Hazardous

Purity

Affinity purified

Appearance form

Lyophilized Powder

Molecular Weight

44 kDa

Solubility (@ RT)

Soluble in PBS

Abbreviation (Lectins Only):

MPL/MPA

Source

Osage orange

Blood Group Specificity

A, B, O (-SA)

Carbohydrate Specificity

Galβ3GalNAc

Conjugate/Tag/Matrix

None

Inhibitory Carbohydrate

Galactose

Divalent Ions

None Required

Mitogenic Activity

Yes

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