4 Hydroxynonenal Polyclonal Antibody, HRP Conjugated
Référence bs-6313R-HRP-20uL
Conditionnement : 20uL
Marque : Bioss
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Applications
Reactivity
| Overview | |
| Catalog # | bs-6313R-HRP |
| Product Name | 4 Hydroxynonenal Polyclonal Antibody, HRP Conjugated |
| Applications | WB, ELISA, IHC-P, IHC-F |
| Reactivity | Others |
| Specifications | |
| Conjugation | HRP |
| Host | Rabbit |
| Source | KLH-conjugated 4-hydroxynonenal |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Subcellular location | Cytoplasm |
| Synonyms | 4-Hydroxy-2-Nonenal; 4Hydroxynonenal; 4-Hydroxynonenal; 4 HNE; 4HNE; 4-HNE; E-4-Hydroxynonenal-dimethylacetal, 4-HNE-DMA. |
| Background | Aldehydic products of lipid peroxidation, such as 4 hydroxynonenal (4 HNE), have been implicated in the etiology of pathological changes under oxidative stress as a key mediator of oxidative stress induced cell death. It is a stable product of lipid peroxidation, is proarrhythmic and may contribute to the cytotoxic effects of oxidative stress 4-HNE has been hypothesized to play a key role in cell signal transduction, in a variety of pathways from cell cycle events to cellular adhesion. |
| Application Dilution | |
| WB | 1:300-5000 |
| ELISA | 1:500-1000 |
| IHC-P | 1:200-400 |
| IHC-F | 1:100-500 |