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Acetylcholine bromide [66-23-9]

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Référence NB-64-10073-1mL

Conditionnement : 1mLx10mM(inDMSO)

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Acetylcholine bromide

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Synonyms:

Catalog No. T20344 Copy Product Info

Purity: 99.93%

Acetylcholine bromide is the bromide salt of acetylcholine. It is an neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.

Cas No. 66-23-9

For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.93%

Color:White

Product Introduction

Acetylcholine bromide AI Summary

Acetylcholine bromide displays diverse bioactivities across various assays. It antagonizes the Neuropeptide Y receptor Y1 with IC50 values exceeding 35000.0 nM in two separate tests. This compound activates the Rab9 promoter at 6309.6 nM and inhibits Influenza NS1 protein function with an IC50 of 2511.9 nM. Additionally, it inhibits human alpha-Glucosidase glycogen cleavage at 9923.7 nM and induces synthetic lethality in tumor cells producing 2HG at 29092.9 nM. For Galanin Receptor 3 (GalR3), it shows an IC50 of 1658.0 nM and also acts as a non-specific activator in a GalR3 counterscreen assay. Acetylcholine bromide activates the transient receptor potential cation channel C4 with an EC50 of 66.7 nM and demonstrates potency in inhibiting the malarial parasite plastid at 14715.7 nM..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Acetylcholine bromide is the bromide salt of acetylcholine. It is an neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.

Chemical Properties

Molecular Weight	226.11
Formula	C₇H₁₆BrNO₂
Cas No.	66-23-9
Smiles	[Br-].CC(=O)OCC[N+](C)(C)C
Relative Density.	1.4246 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Store at low temperature Pure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (243.24 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.4226 mL	22.1131 mL	44.2263 mL	221.1313 mL
5 mM	0.8845 mL	4.4226 mL	8.8453 mL	44.2263 mL
10 mM	0.4423 mL	2.2113 mL	4.4226 mL	22.1131 mL
20 mM	0.2211 mL	1.1057 mL	2.2113 mL	11.0566 mL
50 mM	0.0885 mL	0.4423 mL	0.8845 mL	4.4226 mL
100 mM	0.0442 mL	0.2211 mL	0.4423 mL	2.2113 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

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Keywords

Acetylcholine bromide

Related Tags: Acetylcholine bromide chemical structure | Acetylcholine bromide formula | Acetylcholine bromide molecular weight