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> Acetylcholine bromide [66-23-9]

Acetylcholine bromide [66-23-9]

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Conditionnement : 1g

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Acetylcholine bromide

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Acetylcholine bromide is the bromide salt of acetylcholine. It is an neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.
Acetylcholine bromide
Cas No. 66-23-9
Other Forms of Acetylcholine bromide:
Acetylcholine chloride
Acetylcholine-D16 bromide
Acetylcholine-D9 chloride
Acetylcholine-D4 chloride
Acetylcholine-D4 bromide
Acetylcholine-D13 bromide
Acetylcholine-D9 bromide
Acetylcholine-D4 Bromide (Standard)
Acetylcholine-[D13] Bromide (N,N,N-Trimethyl-D9; 1,1,2,2-D4) (Standard)
Acetylcholine-D4 Chloride (Standard)
Acetylcholine-D9 Chloride (Standard)
Acetylcholine iodide
Acetylcholine
For research use only—not for human use. No sales to individuals. Use as intended only.

Batch Information

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Purity:99.93%
Color:White

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COA HNMR LCMS

Product Introduction

Acetylcholine bromide AI Summary
Acetylcholine bromide displays diverse bioactivities across various assays. It antagonizes the Neuropeptide Y receptor Y1 with IC50 values exceeding 35000.0 nM in two separate tests. This compound activates the Rab9 promoter at 6309.6 nM and inhibits Influenza NS1 protein function with an IC50 of 2511.9 nM. Additionally, it inhibits human alpha-Glucosidase glycogen cleavage at 9923.7 nM and induces synthetic lethality in tumor cells producing 2HG at 29092.9 nM. For Galanin Receptor 3 (GalR3), it shows an IC50 of 1658.0 nM and also acts as a non-specific activator in a GalR3 counterscreen assay. Acetylcholine bromide activates the transient receptor potential cation channel C4 with an EC50 of 66.7 nM and demonstrates potency in inhibiting the malarial parasite plastid at 14715.7 nM..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
Acetylcholine bromide is the bromide salt of acetylcholine. It is an neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.
Chemical Properties
Molecular Weight226.11
FormulaC7H16BrNO2
Cas No.66-23-9
Smiles[Br-].CC(=O)OCC[N+](C)(C)C
Relative Density.1.4246 g/cm3 (Estimated)
Storage & Solubility Information
StorageStore at low temperature Pure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (243.24 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.4226 mL22.1131 mL44.2263 mL221.1313 mL
5 mM0.8845 mL4.4226 mL8.8453 mL44.2263 mL
10 mM0.4423 mL2.2113 mL4.4226 mL22.1131 mL
20 mM0.2211 mL1.1057 mL2.2113 mL11.0566 mL
50 mM0.0885 mL0.4423 mL0.8845 mL4.4226 mL
100 mM0.0442 mL0.2211 mL0.4423 mL2.2113 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.