AKR1C1 antibody
Référence OAGA00409
Conditionnement : 100ul
Marque : Aviva Systems Biology
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AKR1C1 Antibody (OAGA00409)
| Datasheets/Manuals | Printable datasheet for AKR1C1 Antibody (OAGA00409) |
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| Publications | Adrenal lipoma formation via PI(3,4,5)P3/AKT-dependent transdifferentiation of adrenocortical cells into adipocytes Conditional disruption of Nr5a1 directed by Sox9-Cre impairs adrenal development Conditional disruption of Nr5a1 directed by Sox9-Cre impairs adrenal development Preprint — no PubMed record available |
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| Predicted Species Reactivity | Human|Mouse |
| Product Format | Liquid PBS with 0.025% Proclin300 and 20% glycerol |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Conjugation | Unconjugated |
| Application | ICC|IF|IHC|IHC-P|WB |
| Reconstitution and Storage | Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze/thaw cycles. |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human AKR1C1. The exact sequence is proprietary. |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Pig, Rhesus Monkey(>80% identity) |
| Concentration | Varies by lot. See vial for concentration. |
| Application Info | WB: 1:500~3000 ICC/IF: 1:100~1000 IHC-P: 1:100~1000 |
| Gene Symbol | AKR1C1 |
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| Gene Full Name | Aldo-keto reductase family 1 member C1 |
| Alias Symbols | 2-ALPHA-HSD, 20 alpha-hydroxysteroid dehydrogenase, 20-ALPHA-HSD, 20-alpha-hydroxysteroid dehydrogenase, aldo-keto reductase C, aldo-keto reductase family 1 member C1, C9, chlordecone reductase homolog HAKRC, DD1, DD1/DD2, DDH, DDH1, dihydrodiol dehydrogenase 1, dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase, dihydrodiol dehydrogenase 1/2, H-37, HAKRC, HBAB, hepatic dihydrodiol dehydrogenase, high-affinity hepatic bile acid-binding protein, indanol dehydrogenase, MBAB, trans-1,2-dihydrobenzene-1,2-diol dehydrogenase, type II 3-alpha-hydroxysteroid dehydrogenase. |
| NCBI Gene Id | 1645 |
| Protein Name | Aldo-keto reductase family 1 member C1 |
| Description of Target | Converts progesterone to its inactive form, 20-alpha-dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation. |
| Uniprot ID | Q04828 |
| Protein Accession # | NP_001344.2 |
| Molecular Weight | 37 kDa |
