Anti-CD39 Antibody (5S815)
Référence NB-64-125395-100uL
Conditionnement : 100uL
Marque : Neo Biotech
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Anti-CD39 Antibody (5S815)
(Synonyms: ectonucleoside triphosphate diphosphohydrolase 1) Copy Product InfoSynonyms: ectonucleoside triphosphate diphosphohydrolase 1
Catalog No. TMAY-03269 Copy Product Info
Anti-CD39 Antibody (5S815) is a Rabbit antibody targeting CD39. Anti-CD39 Antibody (5S815) can be used in ELISA.
For research use only—not for human use. No sales to individuals. Use as intended only.
Product Information
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-CD39 Antibody (5S815) is a Rabbit antibody targeting CD39. Anti-CD39 Antibody (5S815) can be used in ELISA. |
| Synonyms | ectonucleoside triphosphate diphosphohydrolase 1 |
| Ig Type | Rabbit IgG |
| Clone | 5S815 |
| Reactivity | Mouse |
| Specificity | Mouse CD39/ENTPD1 No cross-reactivity in ELISA with Human ENTPD3 Human ENTPD5 |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD39 (TMPY-02808; P55772; Thr38-Ile478). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | CD39, also known as ENTPD1, belongs to the GDA1/CD39 NTPase family. It is expressed primarily on activated lymphoid cells and can also be detected in endothelial tissues. The vascular isoform and the placental isoform II are present in both placenta and umbilical vein, whereas placental isoform I is present in placenta only. CD39 can hydrolyze both nucleoside triphosphates and diphosphates. It is the dominant ecto nucleotidase of vascular and placental trophoblastic tissues and appears to modulate the functional expression of type 2 purinergic (P2) G protein coupled receptors (GPCRs). CD39 transgenic mice exhibit impaired platelet aggregation, prolonged bleeding times, and resistance to systemic thromboembolism. There is a correlation between ATP hydrolysis and triglycerides in patients with chronic heart disease, suggesting a relationship between ATP diphosphohydrolase and thrombogenesis. In the nervous system, CD39 could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse CD39 protein (TMPY-02808) |
| Antigen Species | Mouse |
| Biology Area | Phosphatases and Regulators |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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