Anti - Clock (dClock)
Référence MBS610475-5x0,1mL
Conditionnement : 5x0.1mL
Marque : MyBiosource
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CLOCK Antibody – Rabbit
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS610475CLOCK, a basic helix-loop-helix (bHLH)/PAS protein, is an important factor in the molecular clock mechanism. Mutations in this protein lead to abnormal circadian behavior and defective transcriptional activity. CLOCK has been shown to interact strongly with… More details
Product Overview
Online Datasheet in PDFProduct Name
Clock, Antibody
Full Product Name
Anti - Clock (dClock)
Product Gene Name
anti-Clock antibody
Product Synonym Names
Clock (dClock)
Isotype
IgG
Host
Rabbit
Species Reactivity
Drosophila
Form/Format
Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
Purity/Purification
Serum
Specificity
Recognizes Drosophila Clock. Drosophila sequence has no significant sequence homology with mammalian Clock or Per proteins.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Chromosome Location
Chromosome: 4; NC_000004.11 (56298660..56412997, complement). Location: 4q12
OMIM
601851
Immunogen
Synthetic peptide corresponding to 17aa within the C-terminus of Drosophila Clock conjugated to KLH.
Type
Pab
Product Categories/Family for anti-Clock antibody
Abs to Circadian Proteins
Applications Tested/Suitable for anti-Clock antibody
ELISA
Application Notes for anti-Clock antibody
Suitable for use in ELISA. Western Blot, though not tested, may potentially be used as an application
ELISA: 1:10,000-1:100,000 using 50-100ng of control peptide/well.
Optimal dilutions to be determined by the researcher.
ELISA: 1:10,000-1:100,000 using 50-100ng of control peptide/well.
Optimal dilutions to be determined by the researcher.
Product References and Citations for anti-Clock antibody
• (1.)Bae K et al (1998) Mol Cell Biol. 18, 6142-6151; Allada R et al (1998) Cell 93, 791-804; Darlington TK et al (1998) Science 280, 1599-1603
Other Notes
Small volumes of anti-Clock antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for Clock purchase
MBS610475 is an antibody targeting Clock. Also known as Anti - Clock (dClock). Reactive in Drosophila. Host: Rabbit.
Additional Details
NCBI/Uniprot data below describe general gene information for Clock. It may not necessarily be applicable to this product.
NCBI Official Full Name
CLOCK
NCBI Official Synonym Full Names
clock homolog (mouse)
NCBI Official Symbol
CLOCK
NCBI Official Synonym Symbols
KAT13D; bHLHe8; KIAA0334
UniProt Protein Name
Circadian locomoter output cycles protein kaput
UniProt Synonym Protein Names
Class E basic helix-loop-helix protein 8
Protein Family
Circadian locomoter output cycles protein
UniProt Gene Name
CLOCK
UniProt Synonym Gene Names
BHLHE8; KIAA0334
UniProt Entry Name
CLOCK_HUMAN
NCBI Protein Information
circadian locomoter output cycles protein kaput; OTTHUMP00000128334; OTTHUMP00000196798; OTTHUMP00000218844; class E basic helix-loop-helix protein 8; circadian locomoter output cycles kaput protein
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-Clock antibody
| Reference Product | PubMed Publications |
|---|---|
| ARNTL antibody | >495 publications with Clock and ARNTL |
| PER3 antibody | >152 publications with Clock and PER3 |
| ARNTL2 antibody | >25 publications with Clock and ARNTL2 |
Pathways associated with anti-Clock antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Circadian Clock Pathway antibodies | Circadian Clock Pathway Diagram |
| Circadian Rhythm - Mammal Pathway antibodies | Circadian Rhythm - Mammal Pathway Diagram |
| Circadian Rhythm - Mammal Pathway antibodies | Circadian Rhythm - Mammal Pathway Diagram |
| Circadian Rhythm Pathway antibodies | Circadian Rhythm Pathway Diagram |
| Diurnally Regulated Genes With Circadian Orthologs Pathway antibodies | Diurnally Regulated Genes With Circadian Orthologs Pathway Diagram |
Diseases associated with anti-Clock antibody
| Disease Name | Pubmed Publications |
|---|---|
| Mental Disorders Antibodies | >1134 publications with Clock and Mental Disorders |
| Central Nervous System Diseases Antibodies | >610 publications with Clock and Central Nervous System Diseases |
| Neurologic Manifestations Antibodies | >552 publications with Clock and Neurologic Manifestations |
| Neoplasms Antibodies | >406 publications with Clock and Neoplasms |
| Cognition Disorders Antibodies | >290 publications with Clock and Cognition Disorders |
| Obesity Antibodies | >152 publications with Clock and Obesity |
| Inflammation Antibodies | >84 publications with Clock and Inflammation |
| Liver Diseases Antibodies | >69 publications with Clock and Liver Diseases |
| Body Weight Changes Antibodies | >56 publications with Clock and Body Weight Changes |
| Intestinal Diseases Antibodies | >53 publications with Clock and Intestinal Diseases |
Organs/Tissues associated with anti-Clock antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >3139 publications with Clock and Brain |
| Blood Antibodies | >1151 publications with Clock and Blood |
| Liver Antibodies | >486 publications with Clock and Liver |
| Heart Antibodies | >449 publications with Clock and Heart |
| Muscle Antibodies | >335 publications with Clock and Muscle |
| Vascular Antibodies | >268 publications with Clock and Vascular |
| Bone Antibodies | >158 publications with Clock and Bone |
| Kidney Antibodies | >135 publications with Clock and Kidney |
| Embryonic Tissue Antibodies | >114 publications with Clock and Embryonic Tissue |
| Skin Antibodies | >113 publications with Clock and Skin |