Anti-LMX1B Antibody
Référence A03296
Conditionnement : 0.1mg
Marque : Boster Bio
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Recommend Dilution
Application
Dilution
Species
LMX1B antibody can be used for detection of LMX1B by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
* It is recommended to optimize the amount of this reagent in each experimental system to achieve the best results.
Product Information
Product Name
Anti-LMX1B Antibody
View all LMX1B Antibodies
View all LMX1B Antibodies
Form
Liquid
Uniprot
Gene ID
Storage & Handling
LMX1B antibody can be stored at 4°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Host
Rabbit
Contents
LMX1B Antibody is supplied in PBS containing ≤0.09% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Rabbit polyclonal LMX1B antibody was raised against a 17 amino acid peptide near the carboxy terminus of human LMX1B. The immunogen is located within amino acids 280 - 330 of LMX1B.
Cross-Reactivity
At least three isoforms are known to exist. This antibody is predicted to not cross-react with LMX1A.
Observed Molecular Weight
68 kDa
Calculated Molecular Weight
44.9 kDa
Background of LMX1B
The LIM homeobox transcription factor 1B (LMX1B) belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1B regulates mid-hindbrain patterning; LMX1B-null mice embryos have a severe reduction in the number of midbrain dopaminergic neurons compared to wild-type. While LMX1B appears to be important for both the development and the survival of dopamine neurons, the related LMX1A is crucial for the differentiation of these cells. However, LMX1A and LMX1B function cooperatively to regulated the proliferation, specification and differentiation of midbrain dopaminergic neuronal progenitors.
Cite This Product
Anti-LMX1B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03296)
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