Mouse anti-Human/Baboon/Cynomolgus Monkey/Rhesus Monkey CD35 Antibody [IHC only]
Anti-Monkey/Rhesus Monkey CD35 Antibody
Anti-Monkey/Rhesus Monkey CD35 Antibody
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Product Description
Specifications
| Size | 7 mL |
| Species | Human |
| Specificity | Other species not known |
| Host Species | Mouse |
| Accession Number | P17927 |
| Gene Id | 1378 |
| Gene Symbols | CR1, C3BR |
| Protein Name / Synonyms | Complement receptor type 1 (C3b/C4b receptor) (CD antigen CD35) |
| Immunogen | Intact human monocytes were used as the immunogen for this CD35 antibody. |
| Isotype | Kappa, IgG1 |
| Purity | Protein G affinity chromatography |
| Concentration (lot specific) | Prediluted in 1X PBS (pH 7.4) with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide, *For IHC use only* |
| Recommended Applications | Prediluted format : incubate for 30 min at RT (2) |
| Domain / Region / Terminus | Cell surface |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
This antibody recognizes a protein of 210-220kDa, which is identified as the complement receptor 1 (CR1), or CD35. The antibody is specific for a site on CD35 that is distal from the C3b-binding site, so that it is unable to block CD35 activity. The CD35 antibody is highly specific and shows no cross-reaction with CR2. The primary function of CD35 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This antibody labels follicular dendritic cells and follicular dendritic cell sarcoma.
Storage
Store the CD35 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.