APC-Cy7 Linked Polyclonal Antibody to Kidney Injury Molecule 1 (Kim1)

Référence MBS2117036-0,1mL

Conditionnement : 0.1mL

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Kidney Injury Molecule 1 (KIM1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2117036
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MBS2117036 is an antibody targeting Kim1. Also known as APC-Cy7 Linked Polyclonal Antibody to Kidney Injury Molecule 1 (Kim1). Reactive in Human, Mouse. Host: Rabbit. More details

Product Overview

Online Datasheet in PDF
Product Name
Kidney Injury Molecule 1 (Kim1), Polyclonal Antibody
Full Product Name
APC-Cy7 Linked Polyclonal Antibody to Kidney Injury Molecule 1 (Kim1)
Product Gene Name
anti-Kim1 antibody
Product Synonym Names
HAVCR1; TIM1; TIMD1; HAVCR; Hepatitis A Virus Cellular Receptor 1; T Cell Immunoglobulin And Mucin Domain-Containing Protein 1; T-cell immunoglobulin mucin receptor 1
Immunogen Sequence
Ser21~Thr2 93
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid; 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
>=100ug/ml (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against Kim1. It has been selected for its ability to recognize Kim1 in immunohistochemical staining and western blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: Kim1 (MBS2111979)
APC-CY7 Conjugated Antibody: Kim1 (MBS2117036)
Matching Pairs
APC-CY7 Conjugated Antibody: Kim1 (MBS2117036)
Immunogen: Kim1 (MBS2122706)
Molecular Weight
364
OMIM
606518
3D Structure
ModBase 3D Structure for Q96D42
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen Sequence
Ser21~Thr293
Cross Reactivity
Human
Conjugation
APC-Cy7

Product Categories/Family for anti-Kim1 antibody

Tumor Immunity; Infection Immunity; Kidney Biomarker
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-Kim1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Other Notes

Small volumes of anti-Kim1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Kim1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Hepatitis A virus cellular receptor 1
NCBI Official Synonym Full Names
hepatitis A virus cellular receptor 1
NCBI Official Symbol
HAVCR1
NCBI Official Synonym Symbols
TIM; KIM1; TIM1; HAVCR; KIM-1; TIM-1; TIMD1; TIMD-1; HAVCR-1
UniProt Protein Name
Hepatitis A virus cellular receptor 1
UniProt Synonym Protein Names
Kidney injury molecule 1; KIM-1; T-cell immunoglobulin and mucin domain-containing protein 1; TIMD-1; T-cell immunoglobulin mucin receptor 1; TIM; TIM-1; T-cell membrane protein 1
UniProt Gene Name
HAVCR1
UniProt Synonym Gene Names
KIM1; TIM1; TIMD1; HAVcr-1; KIM-1; TIMD-1; TIM; TIM-1
UniProt Entry Name
HAVR1_HUMAN
NCBI Protein Information
hepatitis A virus cellular receptor 1; kidney injury molecule 1; T-cell membrane protein 1; T-cell immunoglobulin mucin receptor 1; T-cell immunoglobulin mucin family member 1; T cell immunoglobin domain and mucin domain protein 1

NCBI Summary for Kim1

The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010]
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UniProt Comments for Kim1

TIM-1: May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus. May play a role in kidney injury and repair. Belongs to the immunoglobulin superfamily. TIM family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 5q33.2

Cellular Component: integral to membrane

Molecular Function: viral receptor activity

Biological Process: entry of virus into host cell

Disease: Ige Responsiveness, Atopic
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Kim1 antibody

 Reference Product  PubMed Publications
 LCN2 antibody  >121 publications with Kim1 and LCN2
 IL18 antibody  >71 publications with Kim1 and IL18
 CST3 antibody  >18 publications with Kim1 and CST3
 PKD2 antibody  >3 publications with Kim1 and PKD2
 CD68 antibody  >1 publications with Kim1 and CD68

Diseases associated with anti-Kim1 antibody

 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >219 publications with Kim1 and Kidney Diseases
 Acute Kidney Injury Antibodies  >173 publications with Kim1 and Acute Kidney Injury
 Renal Insufficiency Antibodies  >128 publications with Kim1 and Renal Insufficiency
 Proteinuria Antibodies  >51 publications with Kim1 and Proteinuria
 Inflammation Antibodies  >47 publications with Kim1 and Inflammation
 Hepatitis Antibodies  >46 publications with Kim1 and Hepatitis
 Cardiovascular Diseases Antibodies  >42 publications with Kim1 and Cardiovascular Diseases
 Lung Diseases Antibodies  >32 publications with Kim1 and Lung Diseases
 Necrosis Antibodies  >31 publications with Kim1 and Necrosis
 Disease Models, Animal Antibodies  >30 publications with Kim1 and Disease Models, Animal

Organs/Tissues associated with anti-Kim1 antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >258 publications with Kim1 and Kidney
 Brain Antibodies  >11 publications with Kim1 and Brain
 Intestine Antibodies  >7 publications with Kim1 and Intestine
 Mixed Antibodies  >2 publications with Kim1 and Mixed
 Eye Antibodies  >2 publications with Kim1 and Eye