APC-Cy7 Linked Polyclonal Antibody to Lactoferrin (LTF)
Référence MBS2117031-5mL
Conditionnement : 5mL
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Lactoferrin (LTF) Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2117031SPECIAL PROMOTION: Get FREE Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment
MBS2117031 is an antibody targeting LTF. Also known as APC-Cy7 Linked Polyclonal Antibody to Lactoferrin (LTF). Reactive in Human. Host: Rabbit. More details
Product Overview
Online Datasheet in PDFProduct Name
Lactoferrin (LTF), Polyclonal Antibody
Full Product Name
APC-Cy7 Linked Polyclonal Antibody to Lactoferrin (LTF)
Product Gene Name
anti-LTF antibody
Product Synonym Names
HLF2; LF; GIG12; Lactotransferrin; Growth-inhibiting protein 12; Talalactoferrin; Lfcin-H; Kaliocin-1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid; PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
>=100ug/ml (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against LTF. It has been selected for its ability to recognize LTF in immunohistochemical staining and western blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: LTF (MBS2111978)
APC-CY7 Conjugated Antibody: LTF (MBS2117031)
APC-CY7 Conjugated Antibody: LTF (MBS2117031)
Matching Pairs
APC-CY7 Conjugated Antibody: LTF (MBS2117031)
Immunogen: LTF (MBS2122498)
Immunogen: LTF (MBS2122498)
Molecular Weight
78,182 Da
Chromosome Location
Chromosome: 3; NC_000003.11 (46477496..46506598, complement). Location: 3p21.31
OMIM
150210
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Cross Reactivity
Human
Conjugation
APC-Cy7
Product Categories/Family for anti-LTF antibody
Tumor Immunity; Infection Immunity
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-LTF antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Other Notes
Small volumes of anti-LTF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for LTF. It may not necessarily be applicable to this product.
NCBI Official Full Name
lactoferrin
NCBI Official Synonym Full Names
lactotransferrin
NCBI Official Symbol
LTF
NCBI Official Synonym Symbols
LF; HLF2; GIG12
UniProt Protein Name
Lactotransferrin
UniProt Synonym Protein Names
Growth-inhibiting protein 12; Talalactoferrin
Protein Family
L-shaped tail fiber protein
UniProt Gene Name
LTF
UniProt Synonym Gene Names
GIG12; LF; Lactoferrin; Lfcin-H
UniProt Entry Name
TRFL_HUMAN
NCBI Protein Information
lactotransferrin; talalactoferrin; neutrophil lactoferrin; growth-inhibiting protein 12
NCBI Summary for LTF
This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
Show more UniProt Comments for LTF
LTF: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Belongs to the transferrin family. 2 isoforms of the human protein are produced by alternative promoter.
Protein type: EC 3.4.21.-; Secreted; Protease; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 3p21.31
Cellular Component: extracellular space; specific granule; cytoplasm; extracellular region; nucleus; secretory granule
Molecular Function: heparin binding; protein serine/threonine kinase activator activity; protein binding; ferric iron binding; DNA binding; serine-type endopeptidase activity; iron ion binding
Biological Process: negative regulation of lipopolysaccharide-mediated signaling pathway; interaction with host; ossification; positive regulation of I-kappaB kinase/NF-kappaB cascade; transcription, DNA-dependent; positive regulation of toll-like receptor 4 signaling pathway; antifungal humoral response; proteolysis; iron ion transport; humoral immune response; regulation of cytokine production; activation of NF-kappaB transcription factor; retinal homeostasis; positive regulation of osteoblast differentiation; innate immune response in mucosa; negative regulation of viral genome replication; response to host immune response; positive regulation of osteoblast proliferation; antibacterial humoral response; regulation of tumor necrosis factor production; negative regulation of viral reproduction; iron assimilation by chelation and transport; negative regulation of ATPase activity; negative regulation of apoptosis
Show more Protein type: EC 3.4.21.-; Secreted; Protease; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 3p21.31
Cellular Component: extracellular space; specific granule; cytoplasm; extracellular region; nucleus; secretory granule
Molecular Function: heparin binding; protein serine/threonine kinase activator activity; protein binding; ferric iron binding; DNA binding; serine-type endopeptidase activity; iron ion binding
Biological Process: negative regulation of lipopolysaccharide-mediated signaling pathway; interaction with host; ossification; positive regulation of I-kappaB kinase/NF-kappaB cascade; transcription, DNA-dependent; positive regulation of toll-like receptor 4 signaling pathway; antifungal humoral response; proteolysis; iron ion transport; humoral immune response; regulation of cytokine production; activation of NF-kappaB transcription factor; retinal homeostasis; positive regulation of osteoblast differentiation; innate immune response in mucosa; negative regulation of viral genome replication; response to host immune response; positive regulation of osteoblast proliferation; antibacterial humoral response; regulation of tumor necrosis factor production; negative regulation of viral reproduction; iron assimilation by chelation and transport; negative regulation of ATPase activity; negative regulation of apoptosis
Research Articles on LTF
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Pathways associated with anti-LTF antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Amyloids Pathway antibodies | Amyloids Pathway Diagram |
| Disease Pathway antibodies | Disease Pathway Diagram |
| Latent Infection Of Homo Sapiens With Mycobacterium Tuberculosis Pathway antibodies | Latent Infection Of Homo Sapiens With Mycobacterium Tuberculosis Pathway Diagram |
| Mtb Iron Assimilation By Chelation Pathway antibodies | Mtb Iron Assimilation By Chelation Pathway Diagram |
| Phagosomal Maturation (early Endosomal Stage) Pathway antibodies | Phagosomal Maturation (early Endosomal Stage) Pathway Diagram |
| Response Of Mtb To Phagocytosis Pathway antibodies | Response Of Mtb To Phagocytosis Pathway Diagram |
Diseases associated with anti-LTF antibody
| Disease Name | Pubmed Publications |
|---|---|
| Nervous System Diseases Antibodies | >50 publications with LTF and Nervous System Diseases |
| Neoplasms Antibodies | >39 publications with LTF and Neoplasms |
| Immune System Diseases Antibodies | >26 publications with LTF and Immune System Diseases |
| Inflammation Antibodies | >21 publications with LTF and Inflammation |
| Gastrointestinal Diseases Antibodies | >15 publications with LTF and Gastrointestinal Diseases |
| Drug Toxicity Antibodies | >15 publications with LTF and Drug Toxicity |
| Cardiovascular Diseases Antibodies | >14 publications with LTF and Cardiovascular Diseases |
| Vascular Diseases Antibodies | >11 publications with LTF and Vascular Diseases |
| Lung Diseases Antibodies | >11 publications with LTF and Lung Diseases |
| Heart Diseases Antibodies | >9 publications with LTF and Heart Diseases |
Organs/Tissues associated with anti-LTF antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >100 publications with LTF and Blood |
| Brain Antibodies | >79 publications with LTF and Brain |
| Muscle Antibodies | >48 publications with LTF and Muscle |
| Lung Antibodies | >18 publications with LTF and Lung |
| Skin Antibodies | >14 publications with LTF and Skin |
| Uterus Antibodies | >13 publications with LTF and Uterus |
| Eye Antibodies | >11 publications with LTF and Eye |
| Liver Antibodies | >10 publications with LTF and Liver |
| Bone Antibodies | >7 publications with LTF and Bone |
| Intestine Antibodies | >7 publications with LTF and Intestine |