APC-Linked Polyclonal Antibody to Kynurenine-3-Monooxygenase (KMO)
Référence MBS2125068-1mL
Conditionnement : 1mL
Marque : MyBiosource
Kynurenine-3-Monooxygenase (KMO) Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2125068SPECIAL PROMOTION: Get FREE Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment
MBS2125068 is an antibody targeting KMO. Also known as APC-Linked Polyclonal Antibody to Kynurenine-3-Monooxygenase (KMO). Reactive in Human, Pig. Host: Rabbit. More details
Product Overview
Online Datasheet in PDFProduct Name
Kynurenine-3-Monooxygenase (KMO), Polyclonal Antibody
Full Product Name
APC-Linked Polyclonal Antibody to Kynurenine-3-Monooxygenase (KMO)
Product Gene Name
anti-KMO antibody
Product Synonym Names
Kynurenine-3-Monooxygenase; Kynurenine 3-Hydroxylase
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Pig
Form/Format
Liquid; PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
>=100ug/mL
Please refer to the vial label for the specific concentration. (lot specific)
Please refer to the vial label for the specific concentration. (lot specific)
Specificity
The antibody is a Rabbit polyclonal antibody raised against KMO. It has been selected for its ability to recognize KMO in immunohistochemical staining and western blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months. Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Antibody: KMO (MBS2125068)
Immunogen: KMO (MBS2123870)
Immunogen: KMO (MBS2123870)
Matching Pairs
Unconjugated Antibody: KMO (MBS2125175)
APC Conjugated Antibody: KMO (MBS2125068)
APC Conjugated Antibody: KMO (MBS2125068)
Molecular Weight
55.8kDa
OMIM
603538
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Cross Reactivity
Human
Immunogen
Recombinant KMO (Met1~Ser374) expressed in E Coli
Conjugation
APC
Product Categories/Family for anti-KMO antibody
Enzyme & Kinase
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-KMO antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Application Notes for anti-KMO antibody
WB: 0.5-2ug/mL
IHC: 5-20ug/mL
ICC: 5-20ug/mL
Optimal working dilutions must be determined by end user.
IHC: 5-20ug/mL
ICC: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Other Notes
Small volumes of anti-KMO antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for KMO. It may not necessarily be applicable to this product.
NCBI Official Full Name
kynurenine 3-monooxygenase
NCBI Official Synonym Full Names
kynurenine 3-monooxygenase
NCBI Official Symbol
KMO
NCBI Official Synonym Symbols
dJ317G22.1
UniProt Protein Name
Kynurenine 3-monooxygenase
UniProt Synonym Protein Names
Kynurenine 3-hydroxylase
UniProt Gene Name
KMO
NCBI Protein Information
kynurenine 3-monooxygenase
NCBI Summary for KMO
This gene encodes a mitochondrion outer membrane protein that catalyzes the hydroxylation of L-tryptophan metabolite, L-kynurenine, to form L-3-hydroxykynurenine. Studies in yeast identified this gene as a therapeutic target for Huntington disease. [provided by RefSeq, Oct 2011]
UniProt Comments for KMO
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn) (PubMed:29429898, PubMed:23575632, PubMed:26752518, PubMed:28604669, PubMed:29208702). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract (Probable).
Show more Research Articles on KMO
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-KMO antibody
| Reference Product | PubMed Publications |
|---|---|
| OPN3 antibody | >4 publications with KMO and OPN3 |
| KYNU antibody | >3 publications with KMO and KYNU |
| CHML antibody | >2 publications with KMO and CHML |
| HAAO antibody | >2 publications with KMO and HAAO |
| TDO2 antibody | >1 publications with KMO and TDO2 |
| ACMSD antibody | >1 publications with KMO and ACMSD |
| CCBL2 antibody | >1 publications with KMO and CCBL2 |
Pathways associated with anti-KMO antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Histidine, Lysine, Phenylalanine, Tyrosine, Proline And Tryptophan Catabolism Pathway antibodies | Histidine, Lysine, Phenylalanine, Tyrosine, Proline And Tryptophan Catabolism Pathway Diagram |
| L-kynurenine Degradation Pathway antibodies | L-kynurenine Degradation Pathway Diagram |
| L-tryptophan Degradation III (eukaryotic) Pathway antibodies | L-tryptophan Degradation III (eukaryotic) Pathway Diagram |
| L-tryptophan Degradation XI (mammalian, Via Kynurenine) Pathway antibodies | L-tryptophan Degradation XI (mammalian, Via Kynurenine) Pathway Diagram |
| L-tryptophan Degradation To 2-amino-3-carboxymuconate Semialdehyde Pathway antibodies | L-tryptophan Degradation To 2-amino-3-carboxymuconate Semialdehyde Pathway Diagram |
| Metabolic Pathways antibodies | Metabolic Pathways Diagram |
| Metabolism Pathway antibodies | Metabolism Pathway Diagram |
| Metabolism Of Amino Acids And Derivatives Pathway antibodies | Metabolism Of Amino Acids And Derivatives Pathway Diagram |
| NAD Biosynthesis II (from Tryptophan) Pathway antibodies | NAD Biosynthesis II (from Tryptophan) Pathway Diagram |
| NAD Biosynthesis II (from Tryptophan) Pathway antibodies | NAD Biosynthesis II (from Tryptophan) Pathway Diagram |
Diseases associated with anti-KMO antibody
| Disease Name | Pubmed Publications |
|---|---|
| Inflammation Antibodies | >23 publications with KMO and Inflammation |
| Cardiovascular Diseases Antibodies | >15 publications with KMO and Cardiovascular Diseases |
| Carcinoma Antibodies | >6 publications with KMO and Carcinoma |
| Liver Diseases Antibodies | >5 publications with KMO and Liver Diseases |
| Memory Disorders Antibodies | >5 publications with KMO and Memory Disorders |
| Poisoning Antibodies | >4 publications with KMO and Poisoning |
| Liver Neoplasms Antibodies | >2 publications with KMO and Liver Neoplasms |
| Hepatitis Antibodies | >2 publications with KMO and Hepatitis |
| Kidney Diseases Antibodies | >2 publications with KMO and Kidney Diseases |
| Necrosis Antibodies | >2 publications with KMO and Necrosis |
Organs/Tissues associated with anti-KMO antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >49 publications with KMO and Brain |
| Mixed Antibodies | >7 publications with KMO and Mixed |
| Kidney Antibodies | >5 publications with KMO and Kidney |


