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> Aquaporin 5 (AQP5) Rabbit Polyclonal Antibody

Aquaporin 5 (AQP5) Rabbit Polyclonal Antibody

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Référence AP20601PU-N

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Aquaporin 5 (AQP5) Rabbit Polyclonal Antibody

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SKU
AP20601PU-N
Aquaporin 5 (AQP5) rabbit polyclonal antibody, Aff - Purified
Size:
100 ug
Conjugation:
Unconjugated
 

View other "Aquaporin 5 or NP_001642" antibodies

Specifications
Product Data
Application IHC, WB
Recommended Dilution Western blot: 1/500-1/1000.
Immunohistochemistry on Paraffin Sections: 1/50-1/200.
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide, corresponding to amino acids 220-270 of Human AQP5
Specificity This antibody detects endogenous levels of AQP5 protein.
Buffer PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.2
Concentration 1.0 mg/ml
Purification Affinity Chromatography using epitope-specific immunogen
Conjugation Unconjugated
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size ~ 36 kDa
Gene Name aquaporin 5
Database Link
Background Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. At least ten isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP9. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7 and AQP9 are permeable to urea and glycerol. AQP2 is the only water channel that is activated by vasopressin to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation, and the secretion and reabsorption of cerebrospinal fluid and aqueous humor. In the lung, the 27-kDa AQP5 is responsible for the majority of water transport across the apical membrane of type I alveolar epithelial cells. The gene encoding human AQP5 maps to chromosome 12q13.
Synonyms AQP-5
Reference Data
Protein Categories Membrane Proteins
Protein Families Druggable Genome, Transmembrane
Product Manuals
FAQs
  • Antibody and Western Standard
SDS

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