BAI1 Antibody
Référence MBS8582606-0,1mL-PE
Conditionnement : 0.1mL(PE)
Marque : MyBiosource
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BAI1 Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8582606MBS8582606 is an antibody targeting BAI1. Also known as BAI1 Antibody. Reactive in Human, Mouse, Monkey. Host: Rabbit. Rabbit polyclonal antibody to BAI1 More details
Product Overview
Online Datasheet in PDFProduct Name
BAI1, Polyclonal Antibody
Full Product Name
BAI1 Antibody
Product Gene Name
anti-BAI1 antibody
Product Synonym Names
Brain-specific angiogenesis inhibitor 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Monkey
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of BAI1 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Molecular Weight
173,501 Da
Chromosome Location
Chromosome: 8; NC_000008.10 (143545377..143626368). Location: 8q24.3
OMIM
602682
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human BAI1. The exact sequence is proprietary.
Product Categories/Family for anti-BAI1 antibody
Primary Antibody
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-BAI1 antibody
Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
Application Notes for anti-BAI1 antibody
WB: 1:500-1:1000
IHC: 1:50-1:200
IHC: 1:50-1:200
Other Notes
Small volumes of anti-BAI1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for BAI1. It may not necessarily be applicable to this product.
NCBI Official Full Name
brain-specific angiogenesis inhibitor 1
NCBI Official Synonym Full Names
brain-specific angiogenesis inhibitor 1
NCBI Official Symbol
BAI1
NCBI Official Synonym Symbols
GDAIF
UniProt Protein Name
Brain-specific angiogenesis inhibitor 1
Protein Family
Brain-specific angiogenesis inhibitor
UniProt Gene Name
BAI1
UniProt Entry Name
BAI1_HUMAN
NCBI Protein Information
brain-specific angiogenesis inhibitor 1
NCBI Summary for BAI1
Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas [provided by RefSeq, Jul 2008]
Show more UniProt Comments for BAI1
BAI1: Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Likely to be a potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53 signal in suppression of glioblastoma. May function in cell adhesion and signal transduction in the brain. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Protein type: Receptor, GPCR; Membrane protein, integral; GPCR, family 2; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 8q24.3
Cellular Component: integral to plasma membrane; plasma membrane; integral to membrane; intercellular junction
Molecular Function: G-protein coupled receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway; negative regulation of cell proliferation; negative regulation of angiogenesis; axonogenesis; cell adhesion; signal transduction; peripheral nervous system development
Show more Protein type: Receptor, GPCR; Membrane protein, integral; GPCR, family 2; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 8q24.3
Cellular Component: integral to plasma membrane; plasma membrane; integral to membrane; intercellular junction
Molecular Function: G-protein coupled receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway; negative regulation of cell proliferation; negative regulation of angiogenesis; axonogenesis; cell adhesion; signal transduction; peripheral nervous system development
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-BAI1 antibody
| Reference Product | PubMed Publications |
|---|---|
| MAGI1 antibody | >3 publications with BAI1 and MAGI1 |
| BAIAP2 antibody | >2 publications with BAI1 and BAIAP2 |
| PHYHIP antibody | >1 publications with BAI1 and PHYHIP |
Pathways associated with anti-BAI1 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| P53 Signaling Pathway antibodies | P53 Signaling Pathway Diagram |
| P53 Signaling Pathway antibodies | P53 Signaling Pathway Diagram |
Diseases associated with anti-BAI1 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Brain Diseases Antibodies | >18 publications with BAI1 and Brain Diseases |
| Nervous System Diseases Antibodies | >16 publications with BAI1 and Nervous System Diseases |
| Necrosis Antibodies | >2 publications with BAI1 and Necrosis |
| Kidney Diseases Antibodies | >2 publications with BAI1 and Kidney Diseases |
| Inflammation Antibodies | >1 publications with BAI1 and Inflammation |
| Disease Models, Animal Antibodies | >1 publications with BAI1 and Disease Models, Animal |
Organs/Tissues associated with anti-BAI1 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >47 publications with BAI1 and Brain |
| Nerve Antibodies | >10 publications with BAI1 and Nerve |
| Lung Antibodies | >4 publications with BAI1 and Lung |