Biotin-Linked Polyclonal Antibody to Vitamin D Binding Protein (DBP)
Référence MBS2093799-1mL
Conditionnement : 1mL
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Vitamin D Binding Protein (DBP) Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2093799SPECIAL PROMOTION: Get FREE Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment
MBS2093799 is an antibody targeting DBP. Also known as Biotin-Linked Polyclonal Antibody to Vitamin D Binding Protein (DBP). Reactive in Human, Mouse. Host: Rabbit. More details
Product Overview
Online Datasheet in PDFProduct Name
Vitamin D Binding Protein (DBP), Polyclonal Antibody
Full Product Name
Biotin-Linked Polyclonal Antibody to Vitamin D Binding Protein (DBP)
Product Gene Name
anti-DBP antibody
Product Synonym Names
GC; VDBG; VDBP; Group-Specific Component; Gc-globulin
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Purity/Purification
Antigen-specific Affinity Chromatography.
Concentration
0.32mg/mL (lot specific)
Preparation and Storage
Storage:
Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 24 months.
Stability Test:
thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 24 months.
Stability Test:
thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: DBP (MBS2032543)
Biotin Conjugated Antibody: DBP (MBS2093799)
Biotin Conjugated Antibody: DBP (MBS2093799)
Matching Pairs
Biotin Conjugated Antibody: DBP (MBS2093799)
Immunogen: DBP (MBS2030631)
Immunogen: DBP (MBS2030631)
OMIM
M12654 mRNA
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Source
Antibody labeling
Label
Biotin
Unconjugated Antibody
MBS2032543
Traits
Liquid
Immunogen
Recombinant DBP (Glu395~Leu474) expressed in E.coli (MBS2030631).
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-DBP antibody
Western Blot (WB); Immunohistochemistry (IHC); Immunocytochemistry (ICC); Immunoprecipitation (IP).
Application Notes for anti-DBP antibody
Western blotting: 0.5-2ug/mL;
Immunohistochemistry: 5-20ug/mL;
Immunocytochemistry: 5-20ug/mL;
Optimal working dilutions must be determined by end user.
Immunohistochemistry: 5-20ug/mL;
Immunocytochemistry: 5-20ug/mL;
Optimal working dilutions must be determined by end user.
Other Notes
Small volumes of anti-DBP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for DBP. It may not necessarily be applicable to this product.
NCBI Official Full Name
vitamin D-binding protein isoform 1
NCBI Official Synonym Full Names
GC, vitamin D binding protein
NCBI Official Symbol
GC
NCBI Official Synonym Symbols
DBP; GRD3; VDBG; VDBP; GcMAF; DBP/GC; Gc-MAF; HEL-S-51
UniProt Protein Name
Vitamin D-binding protein
UniProt Synonym Protein Names
Gc protein-derived macrophage activating factor
Protein Family
D site-binding protein
UniProt Gene Name
GC
UniProt Synonym Gene Names
DBP-maf
NCBI Protein Information
vitamin D-binding protein
NCBI Summary for DBP
The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
Show more UniProt Comments for DBP
GC: Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes. Belongs to the ALB/AFP/VDB family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 4q13.3
Cellular Component: cytosol; extracellular region; extracellular space; lysosomal lumen
Molecular Function: actin binding; vitamin D binding; vitamin transporter activity
Biological Process: vitamin D metabolic process; vitamin transport
Disease: Graves Disease, Susceptibility To, 1
Show more Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 4q13.3
Cellular Component: cytosol; extracellular region; extracellular space; lysosomal lumen
Molecular Function: actin binding; vitamin D binding; vitamin transporter activity
Biological Process: vitamin D metabolic process; vitamin transport
Disease: Graves Disease, Susceptibility To, 1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-DBP antibody
| Reference Product | PubMed Publications |
|---|---|
| VDR antibody | >48 publications with DBP and VDR |
| CYP2R1 antibody | >37 publications with DBP and CYP2R1 |
| HPX antibody | >3 publications with DBP and HPX |
| SLC25A18 antibody | >1 publications with DBP and SLC25A18 |
| C5AR1 antibody | >1 publications with DBP and C5AR1 |
| LRP2 antibody | >1 publications with DBP and LRP2 |
Pathways associated with anti-DBP antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Metabolism Pathway antibodies | Metabolism Pathway Diagram |
| Metabolism Of Lipids And Lipoproteins Pathway antibodies | Metabolism Of Lipids And Lipoproteins Pathway Diagram |
| Metabolism Of Steroid Hormones And Vitamin D Pathway antibodies | Metabolism Of Steroid Hormones And Vitamin D Pathway Diagram |
| Vitamin D (calciferol) Metabolism Pathway antibodies | Vitamin D (calciferol) Metabolism Pathway Diagram |
| Vitamin D Synthesis Pathway antibodies | Vitamin D Synthesis Pathway Diagram |
Diseases associated with anti-DBP antibody
| Disease Name | Pubmed Publications |
|---|---|
| Drug Toxicity Antibodies | >1731 publications with DBP and Drug Toxicity |
| Carcinoma Antibodies | >1365 publications with DBP and Carcinoma |
| Brain Diseases Antibodies | >978 publications with DBP and Brain Diseases |
| Inflammation Antibodies | >885 publications with DBP and Inflammation |
| Poisoning Antibodies | >698 publications with DBP and Poisoning |
| Necrosis Antibodies | >598 publications with DBP and Necrosis |
| Liver Diseases Antibodies | >577 publications with DBP and Liver Diseases |
| Kidney Diseases Antibodies | >385 publications with DBP and Kidney Diseases |
| Heart Diseases Antibodies | >346 publications with DBP and Heart Diseases |
| Hypertension Antibodies | >326 publications with DBP and Hypertension |
Organs/Tissues associated with anti-DBP antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >8906 publications with DBP and Blood |
| Liver Antibodies | >2687 publications with DBP and Liver |
| Muscle Antibodies | >1309 publications with DBP and Muscle |
| Kidney Antibodies | >1254 publications with DBP and Kidney |
| Lung Antibodies | >1140 publications with DBP and Lung |
| Heart Antibodies | >921 publications with DBP and Heart |
| Intestine Antibodies | >669 publications with DBP and Intestine |
| Ovary Antibodies | >663 publications with DBP and Ovary |
| Connective Tissue Antibodies | >535 publications with DBP and Connective Tissue |
| Spleen Antibodies | >474 publications with DBP and Spleen |
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