BMX Antibody
Référence MBS8582608-0,1mL-PE
Conditionnement : 0.1mL(PE)
Marque : MyBiosource
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BMX Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8582608MBS8582608 is an antibody targeting BMX. Also known as BMX Antibody. Reactive in Human, Mouse, Rat, Bovine, Dog, Pig. Host: Rabbit. Rabbit polyclonal antibody to BMX More details
Product Overview
Online Datasheet in PDFProduct Name
BMX, Polyclonal Antibody
Full Product Name
BMX Antibody
Product Gene Name
anti-BMX antibody
Product Synonym Names
Cytoplasmic tyrosine-protein kinase BMX; Bone marrow tyrosine kinase gene in chromosome X protein; Epithelial and endothelial tyrosine kinase; ETK; NTK38
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Bovine, Dog, Pig
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of BMX protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Molecular Weight
78,011 Da
Chromosome Location
Chromosome: X; NC_000023.10 (15518900..15574652). Location: Xp22.2
OMIM
300101
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human BMX. The exact sequence is proprietary.
Product Categories/Family for anti-BMX antibody
Primary Antibody
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-BMX antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
Application Notes for anti-BMX antibody
WB: 1:500-1:1000
IHC: 1:50-1:200
IHC: 1:50-1:200
Other Notes
Small volumes of anti-BMX antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for BMX. It may not necessarily be applicable to this product.
NCBI Official Full Name
cytoplasmic tyrosine-protein kinase BMX
NCBI Official Synonym Full Names
BMX non-receptor tyrosine kinase
NCBI Official Symbol
BMX
NCBI Official Synonym Symbols
ETK; PSCTK2; PSCTK3
UniProt Protein Name
Cytoplasmic tyrosine-protein kinase BMX
UniProt Synonym Protein Names
Bone marrow tyrosine kinase gene in chromosome X protein; Epithelial and endothelial tyrosine kinase; ETK; NTK38
Protein Family
Cytoplasmic tyrosine-protein kinase
UniProt Gene Name
BMX
UniProt Synonym Gene Names
ETK
UniProt Entry Name
BMX_HUMAN
NCBI Protein Information
cytoplasmic tyrosine-protein kinase BMX; NTK38 tyrosine kinase; BTK-like on X chromosome; Etk/Bmx cytosolic tyrosine kinase; epithelial and endothelial tyrosine kinase; bone marrow tyrosine kinase gene in chromosome X protein
NCBI Summary for BMX
This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009]
Show more UniProt Comments for BMX
Etk: a tyrosine kinase of the Tec family. Activity is required for IL6-induced differentiation. May play a role in the growth and differentiation of hematopoietic cells. May be involved in signal transduction in endocardial and arterial endothelial cells.
Protein type: EC 2.7.10.2; Protein kinase, tyrosine (non-receptor); Protein kinase, TK; Kinase, protein; TK group; Tec family
Chromosomal Location of Human Ortholog: Xp22.2
Cellular Component: extrinsic to internal side of plasma membrane; cytosol
Molecular Function: signal transducer activity; protein binding; protein-tyrosine kinase activity; metal ion binding; non-membrane spanning protein tyrosine kinase activity; ATP binding; receptor binding
Biological Process: B cell receptor signaling pathway; adaptive immune response; apoptosis; protein amino acid autophosphorylation; innate immune response; mesoderm development; cell adhesion; signal transduction; cell differentiation; T cell receptor signaling pathway; protein amino acid phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway; regulation of cell proliferation; cell structure disassembly during apoptosis
Show more Protein type: EC 2.7.10.2; Protein kinase, tyrosine (non-receptor); Protein kinase, TK; Kinase, protein; TK group; Tec family
Chromosomal Location of Human Ortholog: Xp22.2
Cellular Component: extrinsic to internal side of plasma membrane; cytosol
Molecular Function: signal transducer activity; protein binding; protein-tyrosine kinase activity; metal ion binding; non-membrane spanning protein tyrosine kinase activity; ATP binding; receptor binding
Biological Process: B cell receptor signaling pathway; adaptive immune response; apoptosis; protein amino acid autophosphorylation; innate immune response; mesoderm development; cell adhesion; signal transduction; cell differentiation; T cell receptor signaling pathway; protein amino acid phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway; regulation of cell proliferation; cell structure disassembly during apoptosis
Research Articles on BMX
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-BMX antibody
| Reference Product | PubMed Publications |
|---|---|
| TEC antibody | >67 publications with BMX and TEC |
| BTK antibody | >48 publications with BMX and BTK |
| SRC antibody | >35 publications with BMX and SRC |
| ITK antibody | >30 publications with BMX and ITK |
| STAT3 antibody | >10 publications with BMX and STAT3 |
| PTK2 antibody | >5 publications with BMX and PTK2 |
| STAT1 antibody | >4 publications with BMX and STAT1 |
| PAK1 antibody | >4 publications with BMX and PAK1 |
| TNFRSF1B antibody | >2 publications with BMX and TNFRSF1B |
| CASP3 antibody | >2 publications with BMX and CASP3 |
Pathways associated with anti-BMX antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Angiopoietin Receptor Tie2-mediated Signaling Pathway antibodies | Angiopoietin Receptor Tie2-mediated Signaling Pathway Diagram |
| Apoptosis Pathway antibodies | Apoptosis Pathway Diagram |
| Apoptotic Cleavage Of Cellular Proteins Pathway antibodies | Apoptotic Cleavage Of Cellular Proteins Pathway Diagram |
| Apoptotic Execution Phase Pathway antibodies | Apoptotic Execution Phase Pathway Diagram |
| IL-3 Signaling Pathway antibodies | IL-3 Signaling Pathway Diagram |
| IL-6 Signaling Pathway antibodies | IL-6 Signaling Pathway Diagram |
| Signaling Events Mediated By Focal Adhesion Kinase Pathway antibodies | Signaling Events Mediated By Focal Adhesion Kinase Pathway Diagram |
Diseases associated with anti-BMX antibody
| Disease Name | Pubmed Publications |
|---|---|
| Carcinoma Antibodies | >12 publications with BMX and Carcinoma |
| Inflammation Antibodies | >11 publications with BMX and Inflammation |
| Necrosis Antibodies | >11 publications with BMX and Necrosis |
| Neoplasms, Experimental Antibodies | >8 publications with BMX and Neoplasms, Experimental |
| Cardiovascular Diseases Antibodies | >6 publications with BMX and Cardiovascular Diseases |
| Disease Models, Animal Antibodies | >6 publications with BMX and Disease Models, Animal |
| Breast Neoplasms Antibodies | >5 publications with BMX and Breast Neoplasms |
| Lung Neoplasms Antibodies | >4 publications with BMX and Lung Neoplasms |
| Carcinoma, Hepatocellular Antibodies | >3 publications with BMX and Carcinoma, Hepatocellular |
| Cell Transformation, Neoplastic Antibodies | >3 publications with BMX and Cell Transformation, Neoplastic |
Organs/Tissues associated with anti-BMX antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >42 publications with BMX and Blood |
| Vascular Antibodies | >26 publications with BMX and Vascular |
| Bone Marrow Antibodies | >24 publications with BMX and Bone Marrow |
| Brain Antibodies | >11 publications with BMX and Brain |
| Lung Antibodies | >9 publications with BMX and Lung |
| Muscle Antibodies | >8 publications with BMX and Muscle |
| Liver Antibodies | >8 publications with BMX and Liver |
| Skin Antibodies | >5 publications with BMX and Skin |
| Umbilical Cord Antibodies | >4 publications with BMX and Umbilical Cord |
| Placenta Antibodies | >1 publications with BMX and Placenta |