Orb1225600-25mg | Bobcat339 [2280037-51-4] Biovalley

Bobcat339

SKU: orb1225600

Description

Bobcat339 (Bobcat 339) is a novel cytosine-based TET enzyme inhibitor with IC50 of 33 uM (TET1) and 73 uM (TET2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a; Bobcat339 is a useful tool for investigation of epigenetics and serve as a starting point for new therapeutics that target DNA methylation and gene transcription.

Images & Validation

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Key Properties

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CAS Number	2280037-51-4
MW	297.742
Purity	>98% (HPLC)
Formula	C₁₆H₁₂ClN₃O
Target	DNMT
Solubility	DMSO: Soluble （ < 1 mg/ml refers to the product slightly soluble or insoluble )

Bioactivity

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In Vitro	Bobcat339 (10 μM; 24 hours) significantly reduces global 5hmC levels by inhibiting TET enzyme function in HT-22 cells.

Storage & Handling

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Storage	Storage temperature: -20°C. Stability: ≥ 2 years
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Bobcat 339

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Bobcat339 hydrochloride [orb1689025]
Purity:
99.22% (May vary between batches)
CAS Number:
2436747-44-1
MW:
334.2
Formula:
C₁₆H₁₃Cl₂N₃O
Sizes Available: 5 mg, 2 mg, 100 mg, 1 ml x 10 mM (in DMSO), 25 mg, 10 mg, 50 mg, 200 mg
Bobcat339 [orb1302003]
Purity:
99.67% (May vary between batches)
CAS Number:
2280037-51-4
MW:
297.74
Formula:
C₁₆H₁₂ClN₃O
Sizes Available: 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 1 ml x 10 mM (in DMSO)

Quick Database Links

Gene Symbol

DNMT

Bobcat339 [2280037-51-4]

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