CD49f (CD49f Antigen, Integrin alpha 6, ITGA6, ITGA6B, VLA 6 alpha Subunit, VLA-6) (AP)
Référence MBS6247694-5x0,1mL
Conditionnement : 5x0.1mL
Marque : MyBiosource
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CD49f (CD49f Antigen, Integrin alpha 6, ITGA6, ITGA6B, VLA 6 alpha Subunit, VLA-6) (AP)
Staining of human peripheral blood platelets with RAT ANTI HUMAN CD49f:Azide Free (MCA699XZ)
Staining of human peripheral blood platelets with RAT ANTI HUMAN CD49f:Biotin (MCA699B)
CD49f Antibody – Rat Monoclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6247694MBS6247694 is an antibody targeting CD49f. Also known as CD49f (CD49f Antigen, Integrin alpha 6, ITGA6, ITGA6B, VLA 6 alpha Subunit, VLA-6) (AP). Reactive in Canine, Human, Monkey, Mouse, Porcine, Sheep. Host: Rat. More details
Product Overview
Online Datasheet in PDFProduct Name
CD49f, Monoclonal Antibody
Full Product Name
CD49f (CD49f Antigen, Integrin alpha 6, ITGA6, ITGA6B, VLA 6 alpha Subunit, VLA-6) (AP)
Product Gene Name
anti-CD49f antibody
Product Synonym Names
Integrin alpha chain
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
3H1515
Host
Rat
Species Reactivity
Canine, Human, Monkey, Mouse, Porcine, Sheep
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with Alkaline Phosphatase.
Purity/Purification
Purified by Protein G Affinity Chromatography
Specificity
Recognizes human CD49f. Reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukaemia cells (alpha-6 beta-1). Reported to inhibit platelet adhesion to laminin. Species Crossreactivity: Mouse, canine, porcine, sheep, cynomolgus monkey.
Preparation and Storage
Store at 4 degree C. Do Not Freeze.
Immunogen
BALB/c mouse mammary tumor cells.
Conjugate
AP
Product Categories/Family for anti-CD49f antibody
Antibodies; CD Markers
Applications Tested/Suitable for anti-CD49f antibody
Immunohistochemistry (IHC), Immunoprecipitation (IP)
Product References and Citations for anti-CD49f antibody
1. Soligo, D. et al. (1989) Immunohistochemical reacitivy on bone marrow and tissues of anti-VLA antibodies in the platelet panel, in Leucocyte Typing IV: White Cell Differentiation Antigens. Edited by Knapp, W. et al. Oxford University Press p1029-1032, 2. Workshop of the 4th International Conference on Human Leucocyte Differentiation Antigens Vienna (1989) Workshop number p 055. Oxford University Press, 3. Sonnenberg, A. et al. (1986) Development of mouse mammary gland: identification of stages in differentiation of luminal and myoepithelial cells using monoclonal antibodies and polyvalent antiserum against keratin. Histochem. Cytochem. 34: 1037-1046, 4. Sonnenberg, A. et al. (1987) A complex of platelet glycoproteins Ic and IIa identified by a rat monoclonal antibody J. Biol. Chem. 262: 10376-10383, 5. Helmer, M. et al. (1988) Multiple very late antigen (VLA) heterodimers on platelets. Evidence for distinct VLA-2, VLA-5 (fibronectin receptor), and VLA-6 structures J. Biol. Chem. 263: 7660-7665, 6. Galkowska, H. et al. (1996) Reactivity of antibodies directed against human antigens with surface markers on canine leukocytes. Vet. Immunol. Immunopathol. 53: 329 - 334, 7. Sonnenberg, A. et al. (1988) Laminin receptor on platelets is the integrin VLA-6. Nature. 336: 487 - 489, 8. Sonnenberg, A. et al. (1990) Integrin recognition of different cell-binding fragments of laminin (P1, E3, E8) and evidence that alpha 6 beta 1 but not alpha 6 beta 4 functions as a major receptor for fragments E8. J. Cell. Biol. 110: 2145 - 2155, 9. Sonnenberg, A., et al. (1988) Identification and characterization of a novel antigen complex on mouse mammary tumour cells using a monoclonal antibody against platelet glycoprotein Ic. J. Biol. Chem. 263: 14030 - 14038, 10. Yoshino, N. et al. (2000) Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of Cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies. Exp. Anim.49 (2): 97-110, 11. Sonneberg, A. et al. (1990) The alpha 6 beta 1 (VLA-6) and alpha 6 beta 4 protein complexes: tissue distribution and biochemical properties. J. Cell Sci. 96: 207 - 217.
Other Notes
Small volumes of anti-CD49f antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for CD49f. It may not necessarily be applicable to this product.
Protein Family
Integrin
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.