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> CHAPS [75621-03-3]

CHAPS [75621-03-3]

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Référence orb1307097-500mg

Conditionnement : 500mg

Marque : Biorbyt

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CHAPS

SKU: orb1307097

Description

CHAPS is a zwitterionic, nondenaturing detergent designed for the gentle solubilization of membrane proteins. It is widely used in both in vitro and in vivo research applications, including the study of protein-protein interactions and the purification of functional membrane complexes for structural biology.

Images & Validation

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CHAPS

Key Properties

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CAS Number75621-03-3
MW614.877
Purity99.75% (May vary between batches)
FormulaC32H58N2O7S
SMILESC[C@H](CCC(NCCC[N+](C)(C)CCCS(=O)([O-])=O)=O)[C@H]1CC[C@@]2(19)[C@]3(19)[C@H](O)C[C@]4(19)C[C@H](O)CC[C@]4(C)[C@@]3(19)C[C@H](O)[C@]12C
TargetOthers
SolubilityDMSO:33.33 mg/mL (54.21 mM);H2O:46 mg/mL (74.81 mM)

Bioactivity

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In Vitro
CHAPS detergent is non-denaturing to membrane proteins, can solubilize proteins, disaggregate protein-protein interactions, and is electrically neutral. CHAPS is also useful in ion-exchange chromatography and isoelectric focusing as it is zwitterionic and does not exhibit a net charge between pH 2 to 12. The critical micelle concentration of CHAPS is 6-10mM.

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

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detergent, CHAPS, complexes, Inhibitor, inhibit, protein, surfactant, stabilized, zwitterionic
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  • PUMA BH3 (human) TFA

    PUMA BH3 (human) TFA [orb1980052]

    3049.30

    10 mg, 25 mg, 1 mg, 5 mg
  • CHAPS hydrate

    CHAPS hydrate [orb2942151]

    331717-45-4

    632.9

    C32H60N2O8S

    500 mg
  • CHAPS

    CHAPS [orb1217673]

    >98% (HPLC)

    75621-03-3

    614.88

    C32H58N2O7S

    500 mg, 1 g

Compound Identifiers

PubChem CID
107670 ↗

Key Properties

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Protocol Information