CTPS1 Antibody
Référence MBS7000798-0,1mg
Conditionnement : 0.1mg
Marque : MyBiosource
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Western Blot
All lanes: CTPS1 antibody at 6ug/ml
Lane 1: Hela whole cell lysate
Lane 2: 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 67, 42 kDa
Observed band size: 67 kDa
All lanes: CTPS1 antibody at 6ug/ml
Lane 1: Hela whole cell lysate
Lane 2: 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 67, 42 kDa
Observed band size: 67 kDa
Immunohistochemistry of paraffin-embedded human pancreatic tissue using MBS7000798 at dilution of 1:100
Immunohistochemistry of paraffin-embedded human breast cancer using MBS7000798 at dilution of 1:100
CTPS1 Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7000798MBS7000798 is an antibody targeting CTPS1. Also known as CTPS1 Antibody. Reactive in Human. Host: Rabbit. More details
Product Overview
Online Datasheet in PDFProduct Name
CTPS1, Polyclonal Antibody
Full Product Name
CTPS1 Antibody
Product Gene Name
anti-CTPS1 antibody
Product Synonym Names
CTP synthase 1 (EC 6.3.4.2) (CTP synthetase 1) (UTP--ammonia ligase 1); CTPS1; CTPS
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
>95%, Protein G purified
Preparation and Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Matching Pairs
Unconjugated Antibody: CTPS1 (MBS7000798)
Biotin Conjugated Antibody: CTPS1 (MBS1492040)
Biotin Conjugated Antibody: CTPS1 (MBS1492040)
Matching Pairs
Unconjugated Antibody: CTPS1 (MBS7000798)
HRP Conjugated Antibody: CTPS1 (MBS1493304)
HRP Conjugated Antibody: CTPS1 (MBS1493304)
OMIM
123860
Immunogen
Recombinant Human CTP synthase 1 protein (300-554AA)
Conjugate
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Immunogen Species
Homo sapiens (Human)
Research Area
Signal Transduction
Target Names
CTPS1
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-131474 / sc-101925
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CTPS1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-CTPS1 antibody
WB:1:500-1:5000
IHC:1:20-1:200
IHC:1:20-1:200
Other Notes
Small volumes of anti-CTPS1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for CTPS1. It may not necessarily be applicable to this product.
NCBI Official Full Name
CTP synthase 1 isoform b
NCBI Official Synonym Full Names
CTP synthase 1
NCBI Official Symbol
CTPS1
NCBI Official Synonym Symbols
CTPS; IMD24
UniProt Protein Name
CTP synthase 1
UniProt Synonym Protein Names
CTP synthetase 1; UTP--ammonia ligase 1
Protein Family
CTP synthase
UniProt Gene Name
CTPS1
UniProt Entry Name
PYRG1_HUMAN
NCBI Protein Information
CTP synthase 1
NCBI Summary for CTPS1
This gene encodes an enzyme responsible for the catalytic conversion of UTP (uridine triphosphate) to CTP (cytidine triphospate). This reaction is an important step in the biosynthesis of phospholipids and nucleic acids. Activity of this proten is important in the immune system, and loss of function of this gene has been associated with immunodeficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Show more UniProt Comments for CTPS1
CTPS: the enzyme cytidine-5-prime-triphosphate synthetase converts UTP to CTP. Important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis. The region to which the CTPS gene has been mapped is the location of breakpoints involved in several tumor types.
Protein type: EC 6.3.4.2; Ligase; Motility/polarity/chemotaxis; Nucleotide Metabolism - pyrimidine
Chromosomal Location of Human Ortholog: 1p34.1
Cellular Component: cytosol; membrane
Molecular Function: ATP binding; CTP synthase activity
Biological Process: B cell proliferation; CTP biosynthetic process; glutamine metabolic process; nucleobase, nucleoside and nucleotide interconversion; nucleobase, nucleoside and nucleotide metabolic process; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; response to drug; T cell proliferation
Disease: Immunodeficiency 24
Show more Protein type: EC 6.3.4.2; Ligase; Motility/polarity/chemotaxis; Nucleotide Metabolism - pyrimidine
Chromosomal Location of Human Ortholog: 1p34.1
Cellular Component: cytosol; membrane
Molecular Function: ATP binding; CTP synthase activity
Biological Process: B cell proliferation; CTP biosynthetic process; glutamine metabolic process; nucleobase, nucleoside and nucleotide interconversion; nucleobase, nucleoside and nucleotide metabolic process; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; response to drug; T cell proliferation
Disease: Immunodeficiency 24
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Pathways associated with anti-CTPS1 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Metabolic Pathways antibodies | Metabolic Pathways Diagram |
| Metabolism Pathway antibodies | Metabolism Pathway Diagram |
| Metabolism Of Nucleotides Pathway antibodies | Metabolism Of Nucleotides Pathway Diagram |
| Pyrimidine Metabolism Pathway antibodies | Pyrimidine Metabolism Pathway Diagram |
| Pyrimidine Metabolism Pathway antibodies | Pyrimidine Metabolism Pathway Diagram |
| Pyrimidine Ribonucleotide Biosynthesis, UMP => UDP/UTP,CDP/CTP Pathway antibodies | Pyrimidine Ribonucleotide Biosynthesis, UMP => UDP/UTP,CDP/CTP Pathway Diagram |
| Pyrimidine Ribonucleotide Biosynthesis, UMP => UDP/UTP,CDP/CTP Pathway antibodies | Pyrimidine Ribonucleotide Biosynthesis, UMP => UDP/UTP,CDP/CTP Pathway Diagram |
| Synthesis And Interconversion Of Nucleotide Di- And Triphosphates Pathway antibodies | Synthesis And Interconversion Of Nucleotide Di- And Triphosphates Pathway Diagram |
| UTP And CTP De Novo Biosynthesis Pathway antibodies | UTP And CTP De Novo Biosynthesis Pathway Diagram |
| UTP And CTP De Novo Biosynthesis Pathway antibodies | UTP And CTP De Novo Biosynthesis Pathway Diagram |
Diseases associated with anti-CTPS1 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Cardiovascular Diseases Antibodies | >2 publications with CTPS1 and Cardiovascular Diseases |
| Liver Diseases Antibodies | >1 publications with CTPS1 and Liver Diseases |
| Nervous System Diseases Antibodies | >1 publications with CTPS1 and Nervous System Diseases |
Organs/Tissues associated with anti-CTPS1 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Muscle Antibodies | >2 publications with CTPS1 and Muscle |
| Blood Antibodies | >2 publications with CTPS1 and Blood |
| Vascular Antibodies | >2 publications with CTPS1 and Vascular |
| Liver Antibodies | >1 publications with CTPS1 and Liver |
| Kidney Antibodies | >1 publications with CTPS1 and Kidney |