3' UTR clone of DENN/MADD domain containing 1A (DENND1A) transcript variant 2 for miRNA target validation
Other products for "DENND1A or NM_024820"
Specifications
Product Data
Vector
pMirTarget
Species
Human
Transfection Reporter
RFP
Assay Reporter
Luciferase
E. coli Selection
Kanamycin (25 ug/mL)
Mammalian Cell Selection
Neomycin
Target Symbol
DENND1A
Synonyms
FAM31A; KIAA1608
ACCN
NM_024820
Insert Size
1744 bp
Sequence Data
Insert Sequence
>SC203126 3’UTR clone of NM_024820 The sequence shown below is from the reference sequence of NM_024820. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site
Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Components
The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.
Note
Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1A, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 PubMed 20154091).supplied by OMIM, Nov 2010
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
